Discovery and preclinical development of a therapeutically active nanobody-based chimeric antigen receptor targeting human CD22

McComb, Scott; Arbabi-Ghahroudi, Mehdi; Hay, Kevin A.; Keller, Brian A.; Faulkes, Sharlene; Rutherford, Michael; Nguyen, Tina; Shepherd, Alex; Wu, Cunle; Marcil, Anne; Aubry, Annie; Hussack, Greg; Pinto, Devanand M.; Ryan, Shannon; Raphael, Shalini; van Faassen, Henk; Zafer, Ahmed; Zhu, Qin; Maclean, Susanne; Chattopadhyay, Anindita; Gurnani, Komal; Gilbert, Rénald; Gadoury, Christine; Iqbal, Umar; Fatehi, Dorothy; Jezierski, Anna; Huang, Jez; Pon, Robert A.; Sigrist, Mhairi; Holt, Robert A.; Nelson, Brad H.; Atkins, Harold; Kekre, Natasha; Yung, Eric; Webb, John; Nielsen, Julie S.; Weeratna, Risini D.

doi:10.1016/j.omton.2024.200775

Molecular Therapy: Oncology

2024

DOI: 10.1016/j.omton.2024.200775

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Discovery and preclinical development of a therapeutically active nanobody-based chimeric antigen receptor targeting human CD22

Scott McComb,

Mehdi Arbabi-Ghahroudi,

Kevin A. Hay

et al.

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Discovery and preclinical development of a therapeutically active nanobody-based chimeric antigen receptor targeting human CD22

Cited by 1 publication

References 41 publications

A Flow Cytometry–Based Method for Assessing CAR Cell Binding Kinetics Using Stable CAR Jurkat Cells

A Flow Cytometry–Based Method for Assessing CAR Cell Binding Kinetics Using Stable CAR Jurkat Cells

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