volume 93, issue 0, P2-P-196 2020
DOI: 10.1254/jpssuppl.93.0_2-p-196
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Abstract: Tau is one of the characteristic deposits in Alzheimer's Disease which occurs in neurofibrillary tangles within neurons. Positron-emission tomography (PET) is a nuclear imaging technique, making it possible to detect tau aggregation in AD in vivo, thereby helping to pre-diagnose and trace disease progression. Up to now, many tau tracers have been developed. For example, the first generation tau tracer [ 18 F]AV-1451 and [ 18 F]THK-5351 developed by our group displayed strong uptake in patients' brains. Althoug…

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