Discovery and Development of a Class of New Conversion (PDF) in Friedländer
Condensation of o-aminonitrile with Carbonyl Compounds
Jianyu Duan,
Qi Zhang,
Ziqi Su
et al.
Abstract:Since the discovery of the new conversion, through intramolecular Pinner to Dimroth rearrangement to form a new skeleton product of dihydroquinazolinone in the normal reaction of Friendländer quinoline synthesis of o-aminonitriles and carbonyl compounds, systematic studies have shown that this conversion is a fast and efficient method for the synthesis of nitrogen-containing heterocyclic compounds, especially pyrimidinone derivatives. In 2008, we named this new transformation as a PDF conversion (a new convers… Show more
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