“…Only nine of these OBUs have been formally linked to the production of specific secondary metabolites. These are sal (salinosporamides) (30), slm (salinilactam) (23), cyl (cyclomarins) (31), cya (cyanosporasides) (28), spo (sporolides) (29), arn (arenimycin) (32), rif (rifamycins) (33), lym (lymphostin) (34), and lom (lomaiviticin) (35), whereas two others are predicted to yield enterocin (36) (PKS31) and arenicolide (37) (PKS28) based on bioinformatic analyses. Although there is no evidence that all pathways are functional, the 113 remaining OBUs far exceed the four Salinispora secondary metabolites (arenamides, pacificanones, salinipyrones, and saliniquinones) that have yet to be linked to specific pathways, suggesting that considerable chemical diversity remains to be discovered from this genus.…”