This paper offers a framework for understanding how management decision errors may lead to iatrogenic outcomes. Organizational iatrogenesis is the unintentional genesis of qualitatively different problems due to mistakes like unwise intervention strategies, well-intended work on the wrong problems or ignorance of significant correlations. Iatrogenic outcomes sometimes involve black swan (Taleb, Nassim Nicholas 2007) scenarios. Three error types are well documented in the literature. Type I or "Alpha" errors and Type II or "Beta" errors form the foundation of interpreting data in statistics. Mitroff and Betz (1972) introduced Type III "Error of the Third Kind," a meta-error of focusing upon or solving the "wrong" problem(s). We add innovation error (Type IV), action errors (Type V and Type VI), and the cascading iatrogenic (Type VII) error of the 7th kind, a dangerous source of irreversible organizational iatrogenesis. While many undesirable outcomes result from uncontrollable interaction of exogenous black swans with unavoidable endogenous ignorance, many are the result of controllable endogenous factors like poor choices, faulty tactics, poor vision, "gung-ho" attitudes toward action, lack of patience, ignorance, and faulty data analysis. Our framework clarifies for leaders where and why to drill down in the decision process to lower risk of uncontrollable iatrogenic outcomes.