Discoveries of gastric function with a lattice Boltzmann model of the human stomach

Brasseur, James G.; Pal, Anshuman; Abrahamsson, Bertil

doi:10.1016/s0021-9290(06)84714-7

Cited by 1 publication

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“…The coupled problem involving an actively contracting wall able to be resisted by the fluid within is discussed by Carew and Pedley 18 . Recent fluid–structure interaction (FSI) computations have investigated transport and mixing of the fluid‐mechanically complex contents of the gastrointestinal tract 19,20 …”

Section: Distended Vesselsmentioning

confidence: 99%

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Fluid Flow in Distensible Vessels

Bertram

2009

Clin Exp Pharma Physio

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1. Flow in single vascular conduits is reviewed, divided into distended and deflated vessels. 2. In distended vessels with pulsatile flow, wave propagation and reflection dominate the spatial and temporal distribution of pressure, determining the shape, size and relative timing of measured pressure waveforms, as well as the instantaneous pressure gradient everywhere. Considerable research has been devoted to accessing the information on pathological vascular malformations contained in reflected waves. Slow waves of contraction of vessel wall muscle, responsible for transport of oesophageal, ureteral and gut contents, have also been modelled. 3. The pressure gradient in a vessel drives the flow. Flow rate can be predicted both analytically and numerically, but analytical theory is limited to idealized geometry. The complex geometry of biological system conduits necessitates computation instead. Initially limited to rigid boundaries, numerical methods now include fluid-structure interaction and can simultaneously model solute transport, thus predicting accurately the environment of the mechanosensors and chemosensors at vessel surfaces. 4. Deflated vessels display all phenomena found in distended vessels, but have additional unique behaviours, especially flow rate limitation and flow-induced oscillation. Flow rate limitation is widespread in the human body and has particular diagnostic importance in respiratory investigation. Because of their liquid lining, the pulmonary airways are also characterized by important two-phase flows, where surface tension phenomena create flows and determine the patency and state of collapse of conduits. 5. Apart from the vital example of phonation, sustained self-excited oscillation is largely avoided in the human body. Where it occurs in snoring, it is implicated in the pathological condition of sleep apnoea.

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Section: Distended Vesselsmentioning

confidence: 99%

“…18 Recent fluid-structure interaction (FSI) computations have investigated transport and mixing of the fluid-mechanically complex contents of the gastrointestinal tract. 19,20…”

Section: Peristalsismentioning

confidence: 99%

Fluid Flow in Distensible Vessels

Bertram

2009

Clin Exp Pharma Physio

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Discoveries of gastric function with a lattice Boltzmann model of the human stomach

Cited by 1 publication

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Fluid Flow in Distensible Vessels

Fluid Flow in Distensible Vessels

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