Discontinuation of orthokeratology on eyeball elongation (DOEE)

Cho, P.; Cheung, Sin Wan

doi:10.1016/j.clae.2016.12.002

Cited by 59 publications

(58 citation statements)

References 17 publications

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“…In another study by Cho and Cheung, a subset of orthokeratology‐wearing children from two previous studies agreed to be randomly assigned to either continue wearing orthokeratology for 14 months or to discontinue orthokeratology for seven months and then resume orthokeratology for another seven months. The authors found an increase in axial elongation in children who discontinued orthokeratology lens wear compared to both children still in orthokeratology and children who had never worn orthokeratology.…”

Section: Myopia Controlmentioning

confidence: 99%

Optical changes and visual performance with orthokeratology

Nti

Berntsen

2020

Clinical and Experimental Optometry

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Orthokeratology has undergone drastic changes since first described in the early 1960s. The original orthokeratology procedure involved a series of lenses to flatten the central cornea and was plagued by variable results. The introduction of highly oxygen‐permeable lens materials that can be worn overnight, corneal topography, and reverse‐geometry lens designs revolutionised this procedure. Modern overnight orthokeratology causes rapid, reliable, and reversible reductions in refractive error. With modern designs, patients can wear lenses overnight, remove them in the morning, and see clearly throughout the day without the need for daytime refractive correction. Modern reverse‐geometry lens designs cause central corneal flattening and mid‐peripheral corneal steepening that provides clear foveal vision while simultaneously causing a myopic shift in peripheral retinal defocus. The peripheral myopic retinal defocus caused by orthokeratology is hypothesised to be responsible for reductions in myopia progression in children fitted with these lenses. This paper reviews the changes in orthokeratology lens design that led to the reverse‐geometry orthokeratology lenses that are used today and the optical changes these lenses produce. The optical changes reviewed include changes in refractive error and their time course, high‐ and low‐contrast visual acuity changes, changes in higher‐order aberrations and visual quality metrics, changes in accommodation, and changes in peripheral defocus caused by orthokeratology. The use of orthokeratology for myopia control in children is also reviewed, as are hypothesised connections between orthokeratology‐induced myopic peripheral defocus and slowed myopia progression in children, and safety and complications associated with lens wear. A better understanding of the ocular and optical changes that occur with orthokeratology will be beneficial to both clinicians and patients in making informed decisions regarding the utilisation of orthokeratology. Future research directions with this lens modality are also discussed.

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Section: Myopia Controlmentioning

confidence: 99%

Optical changes and visual performance with orthokeratology

Nti

Berntsen

2020

Clinical and Experimental Optometry

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“…Rebound effect in the context of MC represents a faster axial elongation and increase in refractive error than that expected in a matched group, upon cessation of the MC treatment. This has been shown to various degrees with cessation of both atropine and OK. 115,207 A potential rebound effect following the use of bifocal/ multifocal soft contact lenses for MC has not been studied and warrants investigation.…”

Section: Rebound Effectsmentioning

confidence: 99%

“…It is desirable to evaluate the rebound effect after MC discontinuation to provide practitioners, parents, and patients with realistic expectations on the long term benefits of MC treatments and the ideal duration of the treatment to overcome a potential faster progression after early discontinuation. 207 Ideally, such studies should incorporate a control group, as it is expected that the axial elongation will slow down naturally with age. Communication of these outcomes should be reported in comparison to a randomly assigned, age-matched control population.…”

Section: Rebound Effectsmentioning

confidence: 99%

IMI – Industry Guidelines and Ethical Considerations for Myopia Control Report

Jones

Drobe

González-Meijóme

et al. 2019

Invest. Ophthalmol. Vis. Sci.

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“…Axial length elongation from baseline in A: Hiraoka et al and B: DOEE (Cho and Cheung) studies ( adapted from Hiraoka et al and Cho and Cheung). Error bars represent standard deviation of the mean.…”

Section: Optical Strategies Of Myopia Controlmentioning

confidence: 99%

“…Another area of significance is the effect of discontinuation of treatment. One study, the Discontinuation of Orthokeratology of Eyeball Elongation (DOEE) study, has explored the effects of six months discontinuation of OK on myopia progression . This study involved children who were a part of two previous studies exploring myopia control with OK .…”

Section: Optical Strategies Of Myopia Controlmentioning

confidence: 99%

Optical and pharmacological strategies of myopia control

Kang

2018

Clinical and Experimental Optometry

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Recent increases in global myopia prevalence rates have raised significant concerns as myopia increases the lifelong risk of various sight-threatening ocular conditions. This growing public health burden has generated significant research interests into understanding both its aetiology and developing effective methods to slow down or stop its development, methods collectively termed 'myopia control'. The growing body of research has demonstrated benefits of various optical and pharmacological treatments resulting in myopia control management increasingly becoming a part of main stream clinical practice. This review will discuss the peer-reviewed literature on the efficacy of various myopia control interventions including multifocal spectacles and contact lenses, orthokeratology and pharmaceutical eye drops, as well as potential future research directions.

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Discontinuation of orthokeratology on eyeball elongation (DOEE)

Cited by 59 publications

References 17 publications

Optical changes and visual performance with orthokeratology

Optical changes and visual performance with orthokeratology

IMI – Industry Guidelines and Ethical Considerations for Myopia Control Report

Optical and pharmacological strategies of myopia control

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