Disclosure and Clinical Outcomes Among Young Adolescents Living With HIV in Kenya

Abstract

Purpose: Informing adolescents of their own HIV infection is critical as the number of adolescents living with HIV increases. We assessed the association between HIV disclosure and retention in care and mortality among adolescents aged 10-14 years in Kenya's national program. Methods: We abstracted routinely collected patient-level data for adolescents enrolled into HIV care in 50 health facilities from November 1, 2004, through March 31, 2010. We defined disclosure as any documentation that the adolescent had been fully or partially made aware of his or her HIV status. We compared weighted proportions for categorical variables using χ2 and weighted logistic regression to identify predictors of HIV disclosure; we estimated the probability of LTFU using Kaplan-Meier methods and dying using Cox regression-based test for equality of survival curves.

Parental Disclosure of Own HIV Status to Children in Two Ghanaian Regions; Examining the Determinants within a Child Vulnerability Context

“…However parental disclosure has rarely been investigated in Ghana. This is consistent with how rare the practice of parental own status disclosure is among many HIV positive parents [22] [23].…”

24-month clinical, immuno-virological outcomes and HIV status disclosure in adolescents living with perinatally-acquired HIV in the COHADO cohort, in Togo and Côte d’Ivoire, 2015-2017

“…During follow-up, the cumulative death rate reached 3%. While this seems high, it is lower than that reported in other studies conducted in ALHIV in sub-Saharan Africa, where it ranged from 4-6% [33,51]. Although these rates remain in the same order of magnitude, our lower rate could be explained by the shorter follow-up duration.…”

“…Many studies have reported on how HIV disclosure improves ALHIV clinical, immunological and virological outcomes as well as retention in care [28,32,33,51,52]. In COHADO, we found that HIV disclosure tend to reduce the odds of having a favorable 24-month outcome, though this was not significant.…”

24-month clinical, immune-virological outcomes and HIV status disclosure in adolescents living with perinatally-acquired HIV in the COHADO cohort, in Togo and Côte d’Ivoire, 2015-2017

“…During follow-up, the cumulative death rate reached 3%. While this seems high, it is lower than that reported in other studies conducted in ALHIV in sub-Saharan Africa, where it ranged from 4-6% [33,51]. Although these rates remain in the same order of magnitude, our relative lower rate could be explained by the shorter follow-up duration.…”

“…Many studies have reported on how HIV-disclosure improves ALHIV clinical, immunological and virological outcomes as well as retention in care [28,32,33,51,52]. In COHADO, we found that HIV-disclosure during COHADO tend to reduce the odds of having a favorable 24-month outcome, though this was not signi cant.…”