Introduction:Oral health has an important role in a person's health, however, low public awareness of dental and oral health causes high cases of dental and oral disease in Indonesia, one of which is plaque buildup and caries. Plaque index assessment can be a measuring tool for dental and oral hygiene, namely Patient Hygiene Performance (PHP) by giving a disclosing solution which can stain dental plaque. Disclosing solution, a current synthetic chemical, has an unpleasant taste, sometimes causing allergic reactions, and has the potential to be carcinogenic, so alternatives are needed. Among alternatives of natural materials which can be used is dragon fruit juice, as it has natural anthocyanin content and can help color the plaque. The aim of this research was to determine differences in using synthetic disclosing solution and dragon fruit juice on plaque index using the Halo Indonesia with Dentists (HI BOGI) application. Methods: This type of research was cross-sectional. Technique Cluster random sampling used in this research involved 84 junior high school students in Cimahi (a city in West Java). Results: This research showed that the PHP index through the HI BOGI application obtained a greater average plaque index value when using disclosing solution, namely 1.437, compared to dragon fruit juice, namely 0.907, with p value = 0.000 (significance atp<0,05). Conclusion: There are differences between plaque index measurements using synthetic disclosing solution and red dragon fruit juice using the HI BOGI application for junior high school students in Cimahi.