Disappearance of Microembolic Signals after Heparin in Acute Cerebral Ischemia due to Cyanotic Heart Disease with Polyglobulia

Unusual Neurologic Manifestations of a Patient with Cyanotic Congenital Heart Disease after Phlebotomy

“…Bilateral TCD monitoring showed several microembolic signals (MES) on middle cerebral arteries of both sides which disappeared after anticoagulant therapy. The authors believe that the clinical events may be due to hyperviscosity and microembolization of aggregated red blood cells [ 6 ]. However, in our patient, treatment with heparin infusion did not resolve neurologic episodes which were frequently repeated every few minutes.…”

Dramatic Reduction of Microemboli after Heparin Infusion in Progressing Stroke due to Aortic Arch Atheroma

“…Nevertheless, others reported the coincidence of reduction rate of embolization in patients with acute stroke and therapy with warfarin plus antiplatelet [21] and, more recently, a paper reported the reduction of MES rate after receiving heparin in the acute phase of cardioembolic stroke [22] .…”