Disagreements between disc diffusion, and MIC-based susceptibility categorizations of ertapenem versus ESBL producers

Different antimicrobial susceptibility testing methods to detect ertapenem resistance in enterobacteriaceae: VITEK2, MicroScan, Etest, disk diffusion, and broth microdilution

“…Broth microdilution (BMD) is a well-established, standard method, but it is too laborintensive for use in clinical laboratories (Versalovic et al, 2011;Garcia and Isenberg, 2010). Antimicrobial susceptibility testing for ertapenem can be performed using all of the above methods; however, many laboratories lack the essential experience to do so, and there is little data comparing the efficacies of the different methods (Pailhories et al, 2014;Samuel et al, 2005;Vading et al, 2011).…”