Abstract:Injuries to the limb are the most frequent cause of permanent disability following combat wounds. We reviewed the medical records of 450 soldiers to determine the type of upper limb nerve injuries sustained, the rate of remaining motor and sensory deficits at final follow-up, and the type of Army disability ratings granted. Of 189 soldiers with an injury of the upper limb, 70 had nerve-related trauma. There were 62 men and eight women with a mean age of 25 years (18 to 49). Disabilities due to nerve injuries w… Show more
“…Nerve repair is difficult, with outcomes notably worse the closer to the torso that the nerve is injured 33. The most common complications from upper extremity nerve damage include motor weakness, neuropathic pain, sensory deficit, limb contracture and muscle atrophy 31. Chronic pain is common25 41 and can be difficult to manage even with modern pain-modulating medications 42–46.…”
Haemorrhage is managed through direct pressure and the application of a tourniquet. It is therefore recommended that the minimum coverage should be the most proximal extent to which a tourniquet can be applied. Superimposition of OSPREY brassards over these identified anatomical structures demonstrates that current coverage provided by the brassards could potentially be reduced.
“…Nerve repair is difficult, with outcomes notably worse the closer to the torso that the nerve is injured 33. The most common complications from upper extremity nerve damage include motor weakness, neuropathic pain, sensory deficit, limb contracture and muscle atrophy 31. Chronic pain is common25 41 and can be difficult to manage even with modern pain-modulating medications 42–46.…”
Haemorrhage is managed through direct pressure and the application of a tourniquet. It is therefore recommended that the minimum coverage should be the most proximal extent to which a tourniquet can be applied. Superimposition of OSPREY brassards over these identified anatomical structures demonstrates that current coverage provided by the brassards could potentially be reduced.
“…The age of the sample was 26 (24)(25)(26)(27)(28)(29)(30)(31) years. The majority of the participants were married or living with a partner, had completed at least an upper secondary education programme and were employed.…”
Section: Resultsmentioning
confidence: 99%
“…Furthermore, 21% had neuropathic pain (PainDETECT scores ≥ 19), whereas 51% had mainly nociceptive pain (PainDETECT scores ≤ 12). The Post-traumatic Stress Disorder Checklist-Civilian score was 26 (22)(23)(24)(25)(26)(27)(28)(29)(30)(31), the anxiety score was 4 (2-6.5) and the score for depression was 2 (1-5).…”
The results from the present study suggest that neuropathic pain is related to increased psychological distress and deterioration in self-rated health in injured soldiers.
“…A survey of US combat injuries sustained in a nine month period of Operation Desert Shield and Desert Storm indicated nerve injury accompanied 30% of limb traumas [1]. In a cohort of 450 medically retired, wounded soldiers (injured between October 2001 and January 2005) loss of nerve function was the second leading cause of disability both in frequency and impact severity [3]; and 37% of upper limb injuries within this cohort exhibited nerve dysfunction [4]. Within open tibial fractures resulting from conflicts occurring between 2003 and 2007, 22% involved nerve injury [5].…”
Section: Introductionmentioning
confidence: 99%
“…In fact, nerve dysfunction is the second leading cause of long-term disability in injured service members [3] and is present in 37% of upper limb injuries with disability [4]. Identification and assessment of non-penetrating nerve injury in trauma patients could improve outcome and aid in therapeutic monitoring.…”
Over 30% of combat injuries involve peripheral nerve injury [1] compared to only 3% in civilian trauma [2]. In fact, nerve dysfunction is the second leading cause of long-term disability in injured service members [3] and is present in 37% of upper limb injuries with disability [4]. Identification and assessment of non-penetrating nerve injury in trauma patients could improve outcome and aid in therapeutic monitoring. We report the use of Raman spectroscopy as a noninvasive, non-destructive method for detection of nerve degeneration in intact nerves due to non-penetrating trauma. Nerve trauma was induced via compression and ischemia/reperfusion injury using a combat relevant swine tourniquet model (>3 hours ischemia). Control animals did not undergo compression/ischemia. Seven days post-operatively, sciatic and femoral nerves were harvested and fixed in formalin. Raman spectra of intact, peripheral nerves were collected using a fiber-optic probe with 3 mm diameter spot size and 785 nm excitation. Data was preprocessed, including fluorescence background subtraction, and Raman spectroscopic metrics were determined using custom peak fitting MATLAB® scripts. The abilities of bivariate and multivariate analysis methods to predict tissue state based on Raman spectroscopic metrics are compared. Injured nerves exhibited changes in Raman metrics indicative of 45% decreased myelin content and structural damage (p<<0.01). Axonal and myelin degeneration, cell death and digestion, and inflammation of nerve tissue samples were confirmed via histology. This study demonstrates the non-invasive ability of Raman spectroscopy to detect nerve degeneration associated with non-penetrating injury, relevant to neurapraxic and axonotmetic injuries; future experiments will further explore the clinical utility of Raman spectroscopy to recognize neural injury.
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