Disability due to rheumatic diseases in the city of Junín, Argentina

Fara, Nauan; Recchia, O; Sequeira, Gabriel; Sánchez, Karina Marisol Cando

doi:10.1007/s00296-019-04260-5

Cited by 2 publications

(1 citation statement)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Systemic sclerosis (SSc) is a multi-system connective tissue disease characterized by autoimmunity, microangiopathy and progressive interstitial and vascular fibrosis in the skin and internal organs (2) . The articular involvement, mainly in the feet and hands, is common in SSc (3) , and is associated with a significant disability (4) . It is usually clinically and radiologically evaluated, resulting in an under-estimation of the manifestations such as synovitis and erosions (5) .…”

Section: Introductionmentioning

confidence: 99%

Comparison of Hand Features in Systemic Sclerosis and Rheumatoid Arthritis Patients by Diagnostic Ultrasound and its Correlation to Disease Activity, Clinical and Radiological Findings

Asy

Abdelkareem

Wahab

et al. 2022

SJMS

View full text Add to dashboard Cite

Introduction and Aim: Imaging evaluation of the rheumatoid arthritis and systemic sclerosis represents a significant part in disease evaluation and follow up. However, it had many limitations and new tools are introduced continuously. The current work aimed to compare ultrasound characteristics of the hand involvement in systemic sclerosis (SSc) and rheumatoid arthritis (RA). Patients and methods: The study included 30 SSc and 40 RA patients. All were evaluated by the full history taking, detailed clinical examination, disease activity scores and the health assessment questionnaires were completed. All necessary laboratory investigations were performed. Finally, radiological examination (plain X-rays and ultrasound for joints of hands and wrist) was performed. Results: Patient age ranged from 22 to 58 years, and RA patients were significantly older, with female sex predominance. SSc was of diffuse (30%) and (70%) were of limited type. The disease activity of RA ranged from 2 to 9, while disease activity of SSc ranged between 1.3 to 3.5. In the SSc group, 56.7% had active disease compared to 40% in RA groups. Patients in the SSc group had a degree of disability, while 82.5% of patients in the RA group had mild- to- moderate disability. Ultrasound examination revealed that, synovitis was significantly increased in RA when compared to the SSc group (55.0% vs 23.3%). The sclerosing pattern of tenosynovitis was significantly increased in SSc than the RA group (92.3% vs 0.0% respectively). Results of ultrasound completely coincides with results of MRI. Finally, there was statistically significant, moderate, proportional correlation between ultrasound and each of erythrocyte sedimentation rate (ESR), and disease activity scores. Conclusion: Ultrasound hand examination in scleroderma and RA is more accurate than separate clinical or X-ray examinations. However, it could not completely substitute clinical examination. But it is a suitable add on especially in detection of early disease activity.

show abstract

Section: Introductionmentioning

confidence: 99%

Comparison of Hand Features in Systemic Sclerosis and Rheumatoid Arthritis Patients by Diagnostic Ultrasound and its Correlation to Disease Activity, Clinical and Radiological Findings

Asy

Abdelkareem

Wahab

et al. 2022

SJMS

View full text Add to dashboard Cite

show abstract

Employment of patients with rheumatoid arthritis - a systematic review and meta-analysis

Kirkeskov,

Bray

2023

BMC Rheumatol

View full text Add to dashboard Cite

Background Patients with rheumatoid arthritis (RA) have difficulties maintaining employment due to the impact of the disease on their work ability. This review aims to investigate the employment rates at different stages of disease and to identify predictors of employment among individuals with RA. Methods The study was carried out according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines focusing on studies reporting employment rate in adults with diagnosed RA. The literature review included cross-sectional and cohort studies published in the English language between January 1966 and January 2023 in the PubMed, Embase and Cochrane Library databases. Data encompassing employment rates, study demographics (age, gender, educational level), disease-related parameters (disease activity, disease duration, treatment), occupational factors, and comorbidities were extracted. Quality assessment was performed employing Newcastle–Ottawa Scale. Meta-analysis was conducted to ascertain predictors for employment with odds ratios and confidence intervals, and test for heterogeneity, using chi-square and I2-statistics were calculated. This review was registered with PROSPERO (CRD42020189057). Results Ninety-one studies, comprising of a total of 101,831 participants, were included in the analyses. The mean age of participants was 51 years and 75.9% were women. Disease duration varied between less than one year to more than 18 years on average. Employment rates were 78.8% (weighted mean, range 45.4–100) at disease onset; 47.0% (range 18.5–100) at study entry, and 40.0% (range 4–88.2) at follow-up. Employment rates showed limited variations across continents and over time. Predictors for sustained employment included younger age, male gender, higher education, low disease activity, shorter disease duration, absence of medical treatment, and the absence of comorbidities. Notably, only some of the studies in this review met the requirements for high quality studies. Both older and newer studies had methodological deficiencies in the study design, analysis, and results reporting. Conclusions The findings in this review highlight the prevalence of low employment rates among patients with RA, which increases with prolonged disease duration and higher disease activity. A comprehensive approach combining clinical and social interventions is imperative, particularly in early stages of the disease, to facilitate sustained employment among this patient cohort.

show abstract

Disability due to rheumatic diseases in the city of Junín, Argentina

Cited by 2 publications

References 6 publications

Comparison of Hand Features in Systemic Sclerosis and Rheumatoid Arthritis Patients by Diagnostic Ultrasound and its Correlation to Disease Activity, Clinical and Radiological Findings

Comparison of Hand Features in Systemic Sclerosis and Rheumatoid Arthritis Patients by Diagnostic Ultrasound and its Correlation to Disease Activity, Clinical and Radiological Findings

Employment of patients with rheumatoid arthritis - a systematic review and meta-analysis

Contact Info

Product

Resources

About