Directed Evolution of Acoustic Reporter Genes Using High-Throughput Acoustic Screening
Robert C. Hurt,
Zhiyang Jin,
Mohamed Soufi
et al.
Abstract:A major challenge in the fields of biological imaging and synthetic biology is noninvasively visualizing the functions of natural and engineered cells inside opaque samples such as living animals. One promising technology that addresses this limitation is ultrasound (US), with its penetration depth of several cm and spatial resolution on the order of 100 µm.1Within the past decade, reporter genes for US have been introduced2,3and engineered4,5to link cellular functions to US signals via heterologous expression… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.