Direct pulp capping of permanent teeth in primates using a resorbable form of tricalcium phosphate ceramic

Heller, Alfred L.; Koenigs, Joseph F.; Brilliant, J. David; Melfi, Rudy C.; Driskell, Thomas D.

doi:10.1016/s0099-2399(75)80025-2

Cited by 50 publications

(17 citation statements)

References 6 publications

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“…Osteogen is composed of rod-shaped particles dissimilar in shape and volume but with a maximal length of 0.5 mm and O.I mm in width. The material is different from the resorbable tricalcium phosphate ceramic (Synthos) used by others and which has a powder-like consisteney (5)(6). A calcium hydroxyde product: Dycal (L.D.…”

Section: Materiai and Methodsmentioning

confidence: 99%

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Electron microscope characteristics of dentin repair after hydroxylapatite direct pulp capping in rats

Jaber

Mascrès

Donohue

1991

J Oral Pathology Medicine

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In order to study the osteogenic action of hydroxylapatite (HA) on the dental pulp, a pulp capping experiment was designed using the rat upper molar. Under general anesthesia, molar teeth in 14 male Sprague-Dawley rats were pulp capped with Osteogen (HA) or with Dycal as a control material. After pulp capping, the maxillary molars cavities were restored with amalgam and a pedodontic steel crown was adjusted and sealed over the molar teeth on either side of the maxilla. After 7 days, the areas of necrosis and acute inflammation were more evident in the pulps treated with Dycal than with Osteogen. Hard tissue formation began to appear around dentinal chips in the pulp and extended from the cavity walls into the pulp regardless of the material that was used. Furthermore, this calcified material was scattered throughout the pulp when Osteogen was used, but was not observed in the Dycal treated pulps. The hard tissue formation was thought to be due to the putative fibroblasts and odontoblasts found in the pulp. After 28 days dense dentinal tissue was observed bridging the exposure site when Dycal was used. The dentinal tissues formed with Osteogen was always of a globular type, and showed an irregular distribution. Since Osteogen tends to cause areas of dystrophic calcification in the pulp, its use is not be recommended for pulp capping purposes in humans, because these areas of calcification would make future endodontic treatment difficult.

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Section: Materiai and Methodsmentioning

confidence: 99%

“…Moreover, the results are often contradictory. For example, after pulpotoinies in monkeys, HA capping induced dentinal bridge formation (5). However, in the same animals, when HA was used as a direct pulp-capping agent, it failed to consistently produce complete dentinal bridges, and the dental pulp frequently showed a chronic pulpitis (6).…”

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confidence: 99%

Electron microscope characteristics of dentin repair after hydroxylapatite direct pulp capping in rats

Jaber

Mascrès

Donohue

1991

J Oral Pathology Medicine

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“…In an acidic oral environment, such biocomposites take advantages of the ability of ACPs to release calcium and orthophosphate ions, which potentially can take part in enamel remineralization [ α-TCP and β-TCP: According to the available literature, α-TCP and/or β-TCP (unfortunately, the authors of the publications on the subject not always specify which of them was used) are widely used in dentistry and dentistry-related fields. For example, they are used for augmentation of the surrounding bones [171, [282][283][284][285][286][287][288][289], in maxillofacial surgery [290][291][292][293], as a component of root canal sealers [294], as implant coatings [295], as remineralization [296][297][298][299] and pulpotomy [300] agents, for dental pulp capping [301][302][303][304][305][306], to treat perforations [307,308], as endodontic plugs [309] and to fill various types of bone defects and lesions [310][311][312][313][314][315][316][317][318].…”

Section: Dcpd and Dcpamentioning

confidence: 99%

Calcium Orthophosphates (CaPo ) and Dentistry

Dorozhkin¹

2016

Bioceram Dev Appl

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“…El fosfato tricálcico (FT) componente de la pasta terapéutica anti-A(PTA), ampliamente investigado como agente de cubierta pulpar directa e indirecta con resultados favorables 11,12 . En nuestros estudios 13,14 se utilizó como reparador de los defectos óseos periapicales y dentinarios, con resultados satisfactorios.…”

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Pasta terapéutica anti-A. Producto (2da parte)

Calla

Alcarraz

Gastelú

et al. 2014

Odontol. sanmarquina

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* artículo originalResumen La formulación final que incluye el extracto acuoso de Sangre de grado, excipientes y preservantes; fue denominada Pasta Terapéutica Anti-A (PTA), que se logro después de efectuarse los ensayos de estabilidad acelerada, cada 30 días por espacio de tres meses, que consistió en conservar los frascos conteniendo la formulación de un mismo lote de fabricación a temperatura ambiente y 4 º C de refrigeración y evaluar la consistencia, aspecto, color, olor y actividad bactericida. Esta última se realizó mediante el método de difusión en agar y la técnica de excavación placa cultivo, frente a bacterias Gram positivas y Gram negativas. Los resultados fueron satisfactorios para Gram positivas, como Staphylococcus aureus ATCC 6538, Staphylococcus epidermides ATCC 12228 y bacillus subtilis ATCC 6633, en el caso de Gram negativas solo se observo actividad antimicrobiana frente a Escherichia coli ATCC 8739. mas no así para la Pseudomona aeruginosa. AbstractThe final formulation that includes Sangre de grado watery extract, excipients and preservants; Pasta Terapéutica Anti-A (PTA) was denominated, that profit later to take place the tests of accelerated stability, every 30 days by space of three months, that consisted of conserving the bottles containing the formulation of a same lot of manufacture to room temperature and 4 º C of refrigeration and to evaluate the consistency, aspect, color, scent and bactericidal activity. This last one was made by means of the method of diffusion in agar and the technique of excavation plate culture, in front of positive bacteria negative Odontología SanmarquinaPalabras clave: microbiología oral; biomateriales; Sangre de grado; productos naturales.

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Direct pulp capping of permanent teeth in primates using a resorbable form of tricalcium phosphate ceramic

Cited by 50 publications

References 6 publications

Electron microscope characteristics of dentin repair after hydroxylapatite direct pulp capping in rats

Electron microscope characteristics of dentin repair after hydroxylapatite direct pulp capping in rats

Calcium Orthophosphates (CaPo ) and Dentistry

Pasta terapéutica anti-A. Producto (2da parte)

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