Direct Photoexcitation of Ethynylbenziodoxolones: An Alternative to Photocatalysis for Alkynylation Reactions**

Abstract

Ethynylbenziodoxolones (EBXs) are commonly used as radical traps in photocatalytic alkynylations.H erein, we report that aryl-substituted EBX reagents can be directly activated by visible light irradiation. They act as both oxidants and radical traps,a lleviating the need for ap hotocatalyst in several reported EBX-mediated processes,i ncluding decarboxylative and deboronative alkynylations,t he oxyalkynylation of enamides and the C À Ha lkynylation of THF.F urthermore,t he method could be applied to the synthesis of alkynylated quaternary centers from tertiary alcohols via stable oxalate salts and from tertiary amines via aryl imines.A photocatalytic process using 4CzIPN as an organic dye was also developed for the deoxyalkynylation of oxalates.

The sustainability onion: a panoramic view of a parent concept, its paths, and progeny

“…4 Besides, Alkaraan et al, and Chen et al illustrated that the doctrines of sustainability have percolated into policies and initiatives. 5,6 Examples of such initiatives or projects include Europe's largest publicprivate partnership dedicated to the development of manufacturing sustainable pharmaceuticals (CHEM 21) 7 , the American Chemical Society Pharmaceutical Roundtable (ACS GCIPR) 8,9 , the national centre for competence -sustainable chemical processes through catalyst design 2 (NCCR Catalysis) 10,11,12,13 , that aims to develop technologies to make it possible to base the chemical industry on renewable resources and allow chemical production without waste.…”