Direct medical cost of bipolar disorder: Insights from the FACE-BD longitudinal cohort

Laidi, Charles; Godin, O.; Étain, Bruno; Bellivier, Frank; Elandaloussi, Yannis; Olié, Émilie; Aouizerate, Bruno; Gard, Sébastien; Loftus, J.; Belzeaux, Raoul; Dubertret, Caroline; Laouamri, H.; Passerieux, Christine; Pelletier, A.; Polosan, Mircea; Schwan, Raymund; Samalin, Ludovic; Llorca, Pierre‐Michel; Courtet, Philippe; Durand‐Zaleski, Isabelle; Leboyer, Marion

doi:10.1016/j.jad.2022.02.071

Cited by 3 publications

(2 citation statements)

References 42 publications

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“…However, the costs could be dropped by more than 50% based on two-year follow-up observations for the subgroup with skilled nursing treatment. 82 Notably, in addition to the cost of treatment, impaired academic performance, unemployment, loss of productivity, and reduced interpersonal interactions due to symptoms and cognitive impairment also impose incalculable financial costs on patients. 83 …”

Section: Family Functioningmentioning

confidence: 99%

Functional Alterations in Patients with Bipolar Disorder and Their Unaffected First-Degree Relatives: Insight from Genetic, Epidemiological, and Neuroimaging Data

Zhang,

Chen,

Fang

2023

NDT

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Bipolar disorder (BD) profoundly affects cognitive and psychosocial functioning, leading to a significant illness burden on patients and their families. Genetic factors are predominant in the onset of bipolar disorder and functional impairments. This disorder exhibits a strong family aggregation, with heritability estimates reaching up to 80%. Individuals with BD often experience impaired functioning, especially in significant areas such as physical performance, sleep, cognition, interpersonal interactions, socioeconomic status, family and marital relationships, work and school performance, well-being, and life expectancy. However, patients with different subtypes exhibit significant heterogeneity in social functioning, cognition, and creativity levels. There are notable differences in psychosocial and cognitive function in their unaffected first-degree relatives (UFR) who do not suffer but may carry susceptibility genes compared to healthy control (HC) without a family history. The observations indicate common genetic structures between BD patients and their UFR, which results in varying degrees of functional abnormalities. Therefore, this article mainly provides evidence on cognition, creativity, and psychosocial functioning in patients with BD and their UFR to provide a more comprehensive understanding of this critical topic in the field of BD. By integrating various findings, including clinical data and neuroimaging studies, our article aims to provide insights and valuable information for a deeper exploration of the pathogenesis of BD and the development of more targeted therapeutic strategies in the future.

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Section: Family Functioningmentioning

confidence: 99%

Functional Alterations in Patients with Bipolar Disorder and Their Unaffected First-Degree Relatives: Insight from Genetic, Epidemiological, and Neuroimaging Data

Zhang,

Chen,

Fang

2023

NDT

View full text Add to dashboard Cite

show abstract

“…Relapses cause crises for patients, their families, healthcare services and society. There is evidence that specialist treatment may be effective in terms of reducing relapses, improving quality of life, and reducing health care costs (5). This includes psychoeducation for cases and their families which, as an adjunct strategy to pharmacotherapy in the treatment of BD leads to a reduction in the frequency of relapse, length of hospital stays, and better adherence to drug therapy (6).…”

mentioning

confidence: 99%