A standing problem in low-dimensional electron systems is the nature of the 5/2 fractional quantum Hall (FQH) state: Its elementary excitations are a focus for both elucidating the state's properties and as candidates in methods to perform topological quantum computation. Interferometric devices may be used to manipulate and measure quantum Hall edge excitations. Here we use a small-area edge state interferometer designed to observe quasiparticle interference effects. Oscillations consistent in detail with the Aharonov-Bohm effect are observed for integer quantum Hall and FQH states (filling factors ؍ 2, 5/3, and 7/3) with periods corresponding to their respective charges and magnetic field positions. With these factors as charge calibrations, periodic transmission through the device consistent with quasiparticle charge e/4 is observed at ؍ 5/2 and at lowest temperatures. The principal finding of this work is that, in addition to these e/4 oscillations, periodic structures corresponding to e/2 are also observed at 5/2 and at lowest temperatures. Properties of the e/4 and e/2 oscillations are examined with the device sensitivity sufficient to observe temperature evolution of the 5/2 quasiparticle interference. In the model of quasiparticle interference, this presence of an effective e/2 period may empirically reflect an e/2 quasiparticle charge or may reflect multiple passes of the e/4 quasiparticle around the interferometer. These results are discussed within a picture of e/4 quasiparticle excitations potentially possessing non-Abelian statistics. These studies demonstrate the capacity to perform interferometry on 5/2 excitations and reveal properties important for understanding this state and its excitations.5/2 fractional quantum Hall effect ͉ fractional quantum Hall effect ͉ non-Abelian statistics ͉ topological quantum computation E xperimentally, the fractional quantum Hall (FQH) state at 5/2 ϭ filling factor is anomalous in that it occurs at an even denominator quantum number (1). The state is fragile: It displays a weak quantum Hall effect, requiring temperatures for observation substantially lower than the principal odd denominator states at ϭ 1/3 and 2/3. It has been proposed as either a spin polarized [Moore-Read Pfaffian (2)] or non-spin polarized [Haldane-Rezayi (3)] paired composite fermion state. The fundamental quasiparticle excitations are expected to be charged e/4, and for the Pfaffian state these quasiparticles are to obey non-Abelian statistics. These nonAbelian states may display utility in topological quantum computational schemes (4) To the end of determining the charge, and more importantly the statistics of the quasiparticles, interference devices and their function in displaying the Aharonov-Bohm (A-B) effect at 5/2 have been described theoretically (5-9). Interference devices are typically constructed with nominally 2 adjacent quantum point contacts (qpcs), each able to variably transmit current, and a confinement area between the qpcs (see schematic in Fig. 1). By splitting the cur...