Direct laser writing: Principles and materials for scaffold 3D printing

Selimis, Alexandros; Mironov, Vladimir; Farsari, Maria

doi:10.1016/j.mee.2014.10.001

Cited by 283 publications

(178 citation statements)

References 80 publications

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“…Earlier studies dedicated to pure material structuring by femtosecond laser pulses [16,45] have shown to be complicated and slow. If such pure material can be structured at a relatively high speed (∼mm/s) it would become suitable for biomedical applications, where structure dimensions are in the range of mm-cm [46]. Pure material would guarantee superb biocompatibility, which is a key requirement for tissue engineering.…”

Section: Discussionmentioning

confidence: 99%

Optically Clear and Resilient Free-Form <em>µ</em>-Optics 3D-Printed via Ultrafast Laser Lithography

Jonušauskas

Gailevičius

Mikoliūnaitė

et al. 2016

Preprint

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Abstract:We introduce optically clear and resilient free-form micro-optical components of pure (non-photosensitized) organic-inorganic SZ2080 material made by femtosecond 3D laser lithography (3DLL). This is advantageous for rapid printing of 3D micro-/nanooptics, including their integration directly onto optical fibers. A systematic study on the fabrication peculiarities and quality of resultant structures is performed. Comparison of microlenses' resiliency to CW and femtosecond pulsed exposure is determined. Experimental results prove that pure SZ2080 is ∼3 fold more resistant to high irradiance as compared with a standard photo-sensitized material and can sustain up to 1.91 GW/cm 2 intensity. 3DLL is a promising manufacturing approach for high-intensity micro-optics for emerging fields in astro-photonics and atto-second pulse generation. Additionally, pyrolysis is employed to shrink structures up to 40% by removing organic SZ2080 constituents. This opens a promising route towards downscaling photonic lattices and creation of mechanically robust glass-ceramic structures.

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Section: Discussionmentioning

confidence: 99%

Optically Clear and Resilient Free-Form <em>µ</em>-Optics 3D-Printed via Ultrafast Laser Lithography

Jonušauskas

Gailevičius

Mikoliūnaitė

et al. 2016

Preprint

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“…Due to its pioneering as a printing technique, the first commercial 3D printer was stereo lithographic [61]. Therefore, this technique has been widely used in bioengineering and extensively reviewed [175] [176]. The principle of stereo lithography is based upon photo polymerization of vinyl monomers, which is activated by the decomposition of a photo initiator into free radicals when exposed to UV radiation or visible light [61] [177]- [179].…”

Section: Stereo Lithographymentioning

confidence: 99%

“…Even though high laser scanning velocities are employed in the SLA approach, the ability to simultaneously photo cure all portions of a given slice with DLP significantly speeds cycle times between layers [176]. The SLA or DLP techniques can be used with a wide variety of monomers and resin systems.…”

Section: Stereo Lithographymentioning

confidence: 99%

3D Printed Scaffolds as a New Perspective for Bone Tissue Regeneration: Literature Review

Mota¹,

Silva²,

Lima³

et al. 2016

MSA

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Due to the high incidence of bone fractures in the population, it became necessary to produce scaffolds that are able to assist in tissue regeneration. It is necessary to find an appropriate balance between the mechanical and biological properties, in order to mimic the natural tissue, these properties are directly related to the architecture and their degree of porosity, as well as the size of their pores and their interconnectivity. In this perspective, the 3D printing stands out, where the structure is obtained layer by layer, according to a predetermined computational model which provides a greater control of architecture and scaffold geometry and overcomes, in this way, the limitations of traditional techniques of scaffolds manufacturing. In this way, the objective of this seminar is to present the state of the art of the polymer scaffolds produced by 3D printing and applied to bone tissue regeneration, highlighting the advantages and limitations of this process.

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“…[17][18][19][20] These techniques have shown unique properties for micromachining coating, patterning, and polymerization of various biomaterials for implantable medical devices and regenerative medicine. The optical nature of laserassisted fabrication, such as noncontact, optically selective, high-throughput, and precise processing, provides the capability for high precision processing with submicron resolution (,1 lm).…”

Section: Introductionmentioning

confidence: 99%

Laser-assisted biofabrication in tissue engineering and regenerative medicine

et al. 2016

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Controlling the spatial arrangement of biomaterials and living cells provides the foundation for fabricating complex biological systems. Such level of spatial resolution (less than 10 lm) is difficult to be obtained through conventional cell processing techniques, which lack the precision, reproducibility, automation, and speed required for the rapid fabrication of engineered tissue constructs. Recently, laserassisted biofabrication techniques are being intensively developed with the use of computer-aided processes for patterning and assembling both living and nonliving materials with prescribed 2D or 3D organization. In this review, we discuss laser-assisted fabrication methods, including laser tweezers, multi-photon polymerization, laser-induced forward transfer (LIFT), matrix assisted pulsed laser evaporation (MAPLE), and laser ablation as well as their applications in biological science and biomedical engineering. These advanced technologies enable the precise manipulation of in vitro cellular microenvironments and the ability to engineer functional tissue constructs with high complexity and heterogeneity, which serve in regenerative medicine, pharmacology, and basic cell biology studies.

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Direct laser writing: Principles and materials for scaffold 3D printing

Cited by 283 publications

References 80 publications

Optically Clear and Resilient Free-Form <em>µ</em>-Optics 3D-Printed via Ultrafast Laser Lithography

Optically Clear and Resilient Free-Form <em>µ</em>-Optics 3D-Printed via Ultrafast Laser Lithography

3D Printed Scaffolds as a New Perspective for Bone Tissue Regeneration: Literature Review

Laser-assisted biofabrication in tissue engineering and regenerative medicine

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Direct laser writing: Principles and materials for scaffold 3D printing

Cited by 283 publications

References 80 publications

Optically Clear and Resilient Free-Form <em>&micro;</em>-Optics 3D-Printed via Ultrafast Laser Lithography

Optically Clear and Resilient Free-Form <em>&micro;</em>-Optics 3D-Printed via Ultrafast Laser Lithography

3D Printed Scaffolds as a New Perspective for Bone Tissue Regeneration: Literature Review

Laser-assisted biofabrication in tissue engineering and regenerative medicine

Contact Info

Product

Resources

About

Optically Clear and Resilient Free-Form <em>µ</em>-Optics 3D-Printed via Ultrafast Laser Lithography

Optically Clear and Resilient Free-Form <em>µ</em>-Optics 3D-Printed via Ultrafast Laser Lithography