Direct identification of prohibited substances in cosmetics and foodstuffs using ambient ionization on a miniature mass spectrometry system

Ma, Qiang; Bai, Hua; Li, Wentao; Chao, Wang; Li, Xinshi; Cooks, R. Graham; Ouyang, Zheng

doi:10.1016/j.aca.2016.01.031

Cited by 53 publications

(26 citation statements)

References 77 publications

(92 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Reported applications demonstrate the utility of specific ambient MS techniques in this arena, allowing the direct analysis of utilized surface swabs [24], trace residues [41], bulk evidence [42], and highly complex sample matrices [26,43]. Furthermore, implementing automated spectral library searching and chemical identification on said systems can alleviate the need for field-based data interpretation, allowing the use by nontechnical operators [44].…”

Section: A Review Of the 2009 Census For Publicly Funded Forensicmentioning

confidence: 99%

“…Incorporation of tandem MS data in analyte identification even allows discernment from complex matrices [26,43]. Previous work towards establishing spectral congruence and selectivity compared blind portable MS/MS data to a widely accepted reference library, the 'Wiley Registry of Tandem Mass Spectral Data, MSforID', returning the correct identification for over 30 forensic analytes and evidentiary samples [44].…”

Section: Selectivity Of Analyte Identificationmentioning

confidence: 99%

See 1 more Smart Citation

Analytical Validation of a Portable Mass Spectrometer Featuring Interchangeable, Ambient Ionization Sources for High Throughput Forensic Evidence Screening

Lawton

Traub

Fatigante

et al. 2016

J. Am. Soc. Mass Spectrom.

103

View full text Add to dashboard Cite

Abstract. Forensic evidentiary backlogs are indicative of the growing need for costeffective, high-throughput instrumental methods. One such emerging technology that shows high promise in meeting this demand while also allowing on-site forensic investigation is portable mass spectrometric (MS) instrumentation, particularly that which enables the coupling to ambient ionization techniques. While the benefits of rapid, on-site screening of contraband can be anticipated, the inherent legal implications of field-collected data necessitates that the analytical performance of technology employed be commensurate with accepted techniques. To this end, comprehensive analytical validation studies are required before broad incorporation by forensic practitioners can be considered, and are the focus of this work. Pertinent performance characteristics such as throughput, selectivity, accuracy/precision, method robustness, and ruggedness have been investigated. Reliability in the form of false positive/negative response rates is also assessed, examining the effect of variables such as user training and experience level. To provide flexibility toward broad chemical evidence analysis, a suite of rapidly-interchangeable ion sources has been developed and characterized through the analysis of common illicit chemicals and emerging threats like substituted phenethylamines.

show abstract

Section: A Review Of the 2009 Census For Publicly Funded Forensicmentioning

confidence: 99%

Section: Selectivity Of Analyte Identificationmentioning

confidence: 99%

Analytical Validation of a Portable Mass Spectrometer Featuring Interchangeable, Ambient Ionization Sources for High Throughput Forensic Evidence Screening

Lawton

Traub

Fatigante

et al. 2016

J. Am. Soc. Mass Spectrom.

103

View full text Add to dashboard Cite

show abstract

“…5c) represents an easy means of real time extraction and ionization for MS analysis using lab-scale (Fig. 5d) [66] or miniature mass spectrometers [67]. A liquid-liquid extraction was performed in a nanoESI tube between the biofluid sample and an organic solvent.…”

Section: Future Challenges and Solutionsmentioning

confidence: 99%

Ambient ionization and miniature mass spectrometry system for chemical and biological analysis

Ouyang

2016

TrAC Trends in Analytical Chemistry

Self Cite

101

View full text Add to dashboard Cite

Ambien ionization and miniaturization of mass spectrometers are two fields in mass spectrometry that have advanced significantly in the last decade. The integration of the techniques developed in these two fields is leading to the development of complete miniature analytical systems that can be used for on-site or point-of-care analysis by non-expert users. In this review, we report the current status of development in ambient ionization and miniature mass spectrometers, with an emphasis on those techniques with potential impact on the point-of-care (POC) diagnostics. The challenges in the future development of the integrated systems are discussed with possible solutions presented.

show abstract

“…Furthermore, benzophenone‐1 in nail products was derivatized with N , O ‐bis(trimethylsilyl) trifluoroacetamide, making it amenable to GC–MS analysis . Two simultaneous derivatization and preconcentration approaches have been described for the determination of parabens and cholesterol oxides in shampoo, cream, and lipsticks. Results indicated that good recoveries and high sensitivity were obtained.…”

Section: Sample Preparation Techniquesmentioning

confidence: 99%

Current trends in sample preparation for cosmetic analysis

Zhong

2016

J of Separation Science

View full text Add to dashboard Cite

The widespread applications of cosmetics in modern life make their analysis particularly important from a safety point of view. There is a wide variety of restricted ingredients and prohibited substances that primarily influence the safety of cosmetics. Sample preparation for cosmetic analysis is a crucial step as the complex matrices may seriously interfere with the determination of target analytes. In this review, some new developments (2010-2016) in sample preparation techniques for cosmetic analysis, including liquid-phase microextraction, solid-phase microextraction, matrix solid-phase dispersion, pressurized liquid extraction, cloud point extraction, ultrasound-assisted extraction, and microwave digestion, are presented. Furthermore, the research and progress in sample preparation techniques and their applications in the separation and purification of allowed ingredients and prohibited substances are reviewed.

show abstract

Direct identification of prohibited substances in cosmetics and foodstuffs using ambient ionization on a miniature mass spectrometry system

Cited by 53 publications

References 77 publications

Analytical Validation of a Portable Mass Spectrometer Featuring Interchangeable, Ambient Ionization Sources for High Throughput Forensic Evidence Screening

Analytical Validation of a Portable Mass Spectrometer Featuring Interchangeable, Ambient Ionization Sources for High Throughput Forensic Evidence Screening

Ambient ionization and miniature mass spectrometry system for chemical and biological analysis

Current trends in sample preparation for cosmetic analysis

Contact Info

Product

Resources

About