Direct fluorination of toluene using elemental fluorine in gas/liquid microreactors

Jähnisch, Klaus; Baerns, M.; Hessel, Volker; Ehrfeld, W.; Haverkamp, V.; Löwe, Holger; Wille, Ch.; Guber, A.E.

doi:10.1016/s0022-1139(00)00300-6

Cited by 302 publications

(260 citation statements)

References 15 publications

Supporting

Mentioning

239

Contrasting

Unclassified

Order By: Relevance

“…The interfacial area -to -volume ratio of gas-liquid twophase flow in microchannels was demonstrated to be much higher than that in conventional tubes (Haverkamp et al, 2001;Yue et al, 2006;Fu et al, 2010) and the mass transfer process was greatly enhanced. Therefore, microchannels could be used efficiently and safely in gas absorption, desorption, direct fluorination, hydrogenation and other processes (Tegrotenhuis et al, 2000;Jǎhnisch et al, 2000;Demas et al;2003;Yeong et al, 2004;Kobayashi et al, 2004). There are many reports (Jepsen, 1970;Irandoust and Andersson, 1988;Irandoust et al, 1992;Tortopidis and Bontozoglou, 1997;Bercic and Pintar, 1997;Kreutzer, 2003;Van Baten and Krishna, 2004;Vandu et al, 2005;Yue et al, 2009) on the gas-liquid two-phase mass transfer process.…”

Section: Introductionmentioning

confidence: 99%

Experimental investigation of the liquid volumetric mass transfer coefficient for upward gas-liquid two-phase flow in rectangular microchannels

Zhu

et al. 2010

Braz. J. Chem. Eng.

View full text Add to dashboard Cite

-The gas-liquid two-phase mass transfer process in microchannels is complicated due to the special dynamical characteristics. In this work, a novel method was explored to measure the liquid side volumetric mass transfer coefficient k L a. Pressure transducers were utilized to measure the pressure variation of upward gas-liquid two-phase flow in three vertical rectangular microchannels and the liquid side volumetric mass transfer coefficient k L a was calculated through the Pressure-Volume-Temperature correlation of the gas phase. Carbon dioxide-water, carbon dioxide-ethanol and carbon dioxide-n-propanol were used as working fluids, respectively. The dimensions of the microchannels were 40 μm×240 μm (depth×width), 100 μm×800 μm and 100 μm×2000 μm, respectively. Results showed that the channel diameter and the capillary number influence k L a remarkably and that the maximum value of k L a occurs in the annular flow regime. A new correlation of k L a was proposed based on the Sherwood number, Schmidt number and the capillary number. The predicted values of k L a agreed well with the experimental data.

show abstract

Section: Introductionmentioning

confidence: 99%

Experimental investigation of the liquid volumetric mass transfer coefficient for upward gas-liquid two-phase flow in rectangular microchannels

Zhu

et al. 2010

Braz. J. Chem. Eng.

View full text Add to dashboard Cite

show abstract

“…It has been demonstrated that by using a microstructured reactor the yield could be increased from 50 % to 90 % , as compared to the conventional mode ( Figure 11 ). Jahnisch et al [77] investigated the fl uorination of toluene (using either CH 3 CN or CH 3 OH as solvent) in a falling-fi lm microreactor. The performance of the falling-fi lm microreactor is compared with the conventional laboratory-scale bubble column.…”

Section: Microreactor Technologymentioning

confidence: 99%

Process intensification in green synthesis

Kumar

Nigam

2012

Green Processing and Synthesis

View full text Add to dashboard Cite

In the past few decades there has been an extensive increase in the research for green synthesis processes due to environmental concerns, industrial safety and sustainable development, which makes it an attractive alternative to the conventional synthesis processes. The interest of researchers in the green synthesis processes highlights the importance of understanding the mechanism and the fundamental differences between the different processes. The number of publications in the fi eld of " Green Synthesis " in journals, proceedings, patents, etc. has increased by almost 20 times from 2001 to 2010. The published reports are mainly concerned with green synthesis with catalytic processes, less harmful solvents and process intensifi ed techniques. In the present article, the technological development efforts in the area of green synthesis are summarized. Various techniques for green synthesis process intensifi cation are discussed, e.g., mixers, microreactors, spin disc reactor, oscillated fl ow reactors, microwave irradiation, ultrasonication, multifunctional membranes and coiled fl ow inverter. The applications of green synthesis processes for biofuel, nanoparticle, ionic liquids and pharmaceutical production are also discussed.

show abstract

“…对于急剧放热反应, 反应热可以很快散去, 消除了热斑; 减少了副反应, 且提高了产物的选择性、产率和纯度 [14] . Figure 2 A single-channel microreactor 往往都是采用先将芳胺转化为四氟硼酸重氮盐, 然后再进行分解, 得到芳香单氟化合物 [22] . 最近, Jahnisch 等 …”

Section: 反应效率增加unclassified

Recent Advances in Microfluidic Synthesis

Jin¹,

Dong²,

Zhang³

et al. 2012

Chin. J. Org. Chem.

View full text Add to dashboard Cite

Microfluidic synthesis is a new technology in organic chemistry in recent ten years. Microreactor possesses excellent mass and heat transfer capabilities and much better results, such as significantly higher yields and purity, less reaction time, lower potential danger and greater product selectivity, which could not be reached in traditional reactors, could be achieved. The present paper describes a brief introduction on the conception, merits as well as some advances of microfluidic synthesis.

show abstract

Direct fluorination of toluene using elemental fluorine in gas/liquid microreactors

Cited by 302 publications

References 15 publications

Experimental investigation of the liquid volumetric mass transfer coefficient for upward gas-liquid two-phase flow in rectangular microchannels

Experimental investigation of the liquid volumetric mass transfer coefficient for upward gas-liquid two-phase flow in rectangular microchannels

Process intensification in green synthesis

Recent Advances in Microfluidic Synthesis

Contact Info

Product

Resources

About