The titanium industry has been developing for nearly 70 years since the birth of Ti-6Al-4 V alloy. Due to its high specific strength, high and low-temperature resistance, corrosion resistance and good biocompatibility, titanium alloy is used in aerospace, marine engineering, and biomedical fields. However, the high production cost of titanium alloys currently limits their widespread use like steel and aluminum alloys. Therefore, the low-cost preparation technology for titanium alloys becomes hot research in recent years. This chapter provides a comprehensive overview of low-cost preparation technologies for titanium alloys from four aspects: raw materials, melting, hot working and machining, and advanced technologies. This review would be of interest to scholars in related fields.