Direct Electrochemical Determination of Hydroxymethylfurfural (HMF) and its Application to Honey Samples

Reyes-Salas, E. O.; Manzanilla‐Cano, José A.; Barceló‐Quintal, Manuel H.; Juárez‐Mendoza, Daniel; Reyes‐Salas, Margarita

doi:10.1080/00032710500423476

Cited by 27 publications

(14 citation statements)

References 6 publications

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“…Reyes-Salas et al [ 138 ] reported an electrochemical approach for HMF detection. In this method, a single and sharp reduction signal was created at − 1100 mV versus argentum or argentum chloride, while borate was used as a supporting electrolyte.…”

Section: Detection Methods Of Hmfmentioning

confidence: 99%

5-Hydroxymethylfurfural (HMF) levels in honey and other food products: effects on bees and human health

Shapla

Solayman

Alam

et al. 2018

Chemistry Central Journal

384

224

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An organic compound known as 5-hydroxymethylfurfural (HMF) is formed from reducing sugars in honey and various processed foods in acidic environments when they are heated through the Maillard reaction. In addition to processing, storage conditions affect the formation HMF, and HMF has become a suitable indicator of honey quality. HMF is easily absorbed from food through the gastrointestinal tract and, upon being metabolized into different derivatives, is excreted via urine. In addition to exerting detrimental effects (mutagenic, genotoxic, organotoxic and enzyme inhibitory), HMF, which is converted to a non-excretable, genotoxic compound called 5-sulfoxymethylfurfural, is beneficial to human health by providing antioxidative, anti-allergic, anti-inflammatory, anti-hypoxic, anti-sickling, and anti-hyperuricemic effects. Therefore, HMF is a neo-forming contaminant that draws great attention from scientists. This review compiles updated information regarding HMF formation, detection procedures, mitigation strategies and effects of HMF on honey bees and human health.

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Section: Detection Methods Of Hmfmentioning

confidence: 99%

5-Hydroxymethylfurfural (HMF) levels in honey and other food products: effects on bees and human health

Shapla

Solayman

Alam

et al. 2018

Chemistry Central Journal

384

224

View full text Add to dashboard Cite

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“…In the scan rate study, it is observed that the reduction potentials of the analytes are shifted to a more negative region given an increase in the scan rate while no anodic peaks are seen in the reverse sweep. The process involving the reduction of furfural and HMF produces furfurylic alcohol and 2,5 ‐ bis(hydroxymethyl)furan respectively, and entails the consumption of two electrons in each reaction .…”

Section: Resultsmentioning

confidence: 99%

Determination of furanic aldehydes in sugarcane bagasse by high‐performance liquid chromatography with pulsed amperometric detection using a modified electrode with nickel nanoparticles

Silva

Beluomini

Stradiotto

2015

J of Separation Science

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A glassy carbon electrode chemically modified with nickel nanoparticles coupled with reversed-phase chromatography with pulsed amperometric detection was used for the quantitative analysis of furanic aldehydes in a real sample of sugarcane bagasse hydrolysate. Chromatographic separation was carried out in isocratic conditions (acetonitrile/water, 1:9) with a flow rate of 1.0 mL/min, a detection potential of -50 mV vs. Pd, and the process was completed within 4 min. The analytical curves presented limits of detection of 4.0 × 10 mol/L and 4.3 × 10 mol/L, limits of quantification of 1.3 × 10 and 1.4 × 10 mol/L, amperometric sensitivities of 2.2 × 10 nA mol/L and 2.7 × 10 nA mol/L for furfural and 5-hydroxymethylfurfural, respectively. The values obtained in this sample by the standard addition method were 1.54 ± 0.02 g/kg for 5-hydroxymethylfurfural and 11.5 ± 0.2 g/kg for furfural. The results demonstrate that this new proposed method can be used for the quick detection of furanic aldehydes without the interference of other electroactive species, besides having other remarkable merits that include excellent peak resolution, analytical repeatability, sensitivity, and accuracy.

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“…On the other hand, the RP-HPLC determination is more accurate than the spectrophotometric ones but it is quite slow. In addition to these, other procedures based on separation techniques, such as RP-HPLC-UV [21] or micellar electrokinetic capillary chromatography (MEKC) [22], electrochemical methods, such as differential pulse polarography (DPP) [23] and square wave voltammetry (SWV) [24,25], or sensors [26,27] were used. Spectroscopic approaches were also reported, including a Winkler-based automated flow injection protocol [28] or a recent method based on the HMF derivatization with the Seliwanoff reagent [29].…”

Section: Introductionmentioning

confidence: 99%

Electrochemical Determination of the “Furanic Index” in Honey

et al. 2021

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5-(hydroxymethyl)furan-2-carbaldehyde, better known as hydroxymethylfurfural (HMF), is a well-known freshness parameter of honey: although mostly absent in fresh samples, its concentration tends to increase naturally with aging. However, high quantities of HMF are also found in fresh but adulterated samples or honey subjected to thermal or photochemical stresses. In addition, HMF deserves further consideration due to its potential toxic effects on human health. The processes at the origin of HMF formation in honey and in other foods, containing saccharides and proteins—mainly non-enzymatic browning reactions—can also produce other furanic compounds. Among others, 2-furaldehyde (2F) and 2-furoic acid (2FA) are the most abundant in honey, but also their isomers (i.e., 3-furaldehyde, 3F, and 3-furoic acid, 3FA) have been found in it, although in small quantities. A preliminary characterization of HMF, 2F, 2FA, 3F, and 3FA by cyclic voltammetry (CV) led to hypothesizing the possibility of a comprehensive quantitative determination of all these compounds using a simple and accurate square wave voltammetry (SWV) method. Therefore, a new parameter able to provide indications on quality of honey, named “Furanic Index” (FI), was proposed in this contribution, which is based on the simultaneous reduction of all analytes on an Hg electrode to ca. −1.50 V vs. Saturated Calomel Electrode (SCE). The proposed method, validated, and tested on 10 samples of honeys of different botanical origin and age, is fast and accurate, and, in the case of strawberry tree honey (Arbutus unedo), it highlighted the contribution to the FI of the homogentisic acid (HA), i.e., the chemical marker of the floral origin of this honey, which was quantitatively reduced in the working conditions. Excellent agreement between the SWV and Reverse-Phase High-Performance Liquid Chromatography (RP-HPLC) data was observed in all samples considered.

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Direct Electrochemical Determination of Hydroxymethylfurfural (HMF) and its Application to Honey Samples

Cited by 27 publications

References 6 publications

5-Hydroxymethylfurfural (HMF) levels in honey and other food products: effects on bees and human health

5-Hydroxymethylfurfural (HMF) levels in honey and other food products: effects on bees and human health

Determination of furanic aldehydes in sugarcane bagasse by high‐performance liquid chromatography with pulsed amperometric detection using a modified electrode with nickel nanoparticles

Electrochemical Determination of the “Furanic Index” in Honey

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