Direct effects of casein phosphopeptides on growth and differentiation of in vitro cultured osteoblastic cells (MC3T3-E1)

Tulipano, Giovanni; Bulgari, Omar; Chessa, S.; Nardone, A.; Caroli, Anna

doi:10.1016/j.regpep.2009.11.018

Cited by 36 publications

(20 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…CPPs have also been associated with improved dietary bioavailability of bivalent cations and as a consequence they may play a major role in modulating mineral uptake and bone formation [Meisel and Frister, 1988;FitzGerald, 1998]. Therefore, the utilization of CPPs to improve bone health has been the subject of much research [FitzGerald, 1998;Gueguen and Pointillart, 2000;Tulipano et al, 2010]. CPPs have also been associated with an improvement in oral health, notably for their role in promoting remineralisation of dental enamel, thereby combating the development of dental caries [Reynolds, 1997b;FitzGerald, 1998;Elsayad et al, 2009;Rehder Neto et al, 2009].…”

Section: Potential Of Caseinophosphopeptides As Natural Remineralisinmentioning

confidence: 99%

Biofunctional Properties of Caseinophosphopeptides in the Oral Cavity

Nongonierma

Fitzgerald

2012

Caries Res

View full text Add to dashboard Cite

Caseinophosphopeptides (CPPs), bioactive peptides released from caseins, have the ability to enhance bivalent mineral solubility. This is relevant to numerous biological functions in the oral cavity (promotion of tooth enamel remineralisation, prevention of demineralisation and buffering of plaque pH). Therefore, CPPs may play a positive role as prophylactic agents for caries, enamel erosion and regression of white spot lesions. Most in vitro and in situ studies demonstrate strong evidence for the bioactivity of CPPs in the oral cavity. Nevertheless, relatively little is known concerning their use as adjuvants for oral health and more particularly regarding their long-term effects on oral health.

show abstract

Section: Potential Of Caseinophosphopeptides As Natural Remineralisinmentioning

confidence: 99%

Biofunctional Properties of Caseinophosphopeptides in the Oral Cavity

Nongonierma

Fitzgerald

2012

Caries Res

View full text Add to dashboard Cite

show abstract

“…Donida et al (2009) reported that a CN-derived hydrolysate containing CPP modulates calcium uptake and the differentiation pathways in human osteoblast-like cells. Tulipano et al (2010) demonstrated that CPP may directly affect osteoblast-like cell growth, calcium uptake, and ultimately calcium deposition in the extracellular matrix, either with stimulatory or inhibitory effects.…”

Section: Benefits From Milk: Some Experimental Detailsmentioning

confidence: 99%

Invited review: Dairy intake and bone health: A viewpoint from the state of the art

Caroli

Poli²,

Ricotta

et al. 2011

Journal of Dairy Science

143

View full text Add to dashboard Cite

“…Milk proteins represent a reservoir for a wide variety of bioactive peptides, could affect milk nutritional value [22]. The activity of biopeptides might be affected by amino-acid exchanges or deletions resulting from gene mutations and thus linked to particular breeds [23][24][25]. Thus, the reason for preserving a particular breed can be related to the importance of conserving biological components of particular significance from a nutritional point of view.…”

Section: Endangered Livestock and In Situ Conservation Strategiesmentioning

confidence: 99%

Conservation of endangered animals: From biotechnologies to digital preservation

Pizzi¹,

Caroli²,

Landini³

et al. 2013

View full text Add to dashboard Cite

In the recent years, the number of endangered animals, both referred to livestock and wild species, has grown enormously. The "livestock" term refers to animals domesticated for producing commodities for man such as food, fiber and draught. Livestock biodiversity is integral to our culture, history, environment, and economy. Thousands of livestock breeds have evolved over time to suit particular environments and farming systems. Conservation and analyses of these genetic resources rely on demographic characterization and correct breeding schemes. In addition, molecular genetic studies allow to identify and monitor the genetic diversity within and across breeds and to reconstruct their evolution history. The conservation of livestock variability is also a crucial element in order to preserve and valorise specific nutritional and nutraceutical properties of animal products. Efficient ex situ and in situ conservation strategies, as well as the creation of bio-banks and specific biotechnological and bioinformatics tools for genetic analyses and digital preservation, are obligatory requirements in order to implement an appropriate action for the conservation of animal biodiversity. The main issues concerning different species are summarised, with particular reference to the livestock biodiversity still existing. Some examples of ex situ conservation strategies, which mainly refer to cryoconservation of semen, ova, embryos or tissues, developed in Italy, are presented, and the different actions in defense of Animal Genetic Resources (AnGR) developed within the European Community are illustrated. Interestingly, the same strategies for biological and digital analyses and preservation of livestock biodiversity can be exported to wild endangered animals in order to plan a correct conservation and repopulation of the species. Furthermore, the European Union has set up the guidelines to safeguard the biodiversity and to combat the extinction of animal species, and has made the protection of biodiversity and ecosystems one of the main objectives of the Sixth Environment Action Programme.

show abstract

Direct effects of casein phosphopeptides on growth and differentiation of in vitro cultured osteoblastic cells (MC3T3-E1)

Cited by 36 publications

References 29 publications

Biofunctional Properties of Caseinophosphopeptides in the Oral Cavity

Biofunctional Properties of Caseinophosphopeptides in the Oral Cavity

Invited review: Dairy intake and bone health: A viewpoint from the state of the art

Conservation of endangered animals: From biotechnologies to digital preservation

Contact Info

Product

Resources

About