Direct current pulse train actuation to enhance droplet control in digital microfluidics

Abstract

The effective operation of a digital microfluidic (DMF) device depends on its ability to actuate droplets. Pulse width modulation of actuating signals (DC pulse train actuation) is proposed as a practical digital implementation and enhanced droplet manipulation technique. Experimental and simulation results demonstrate the efficacy of droplet incremental displacement and velocity control by modulating the width of each actuation pulse. This will in turn enable the control of the non-linear droplet transport dynamics to minimize droplet position overshoot, deformation, and fragmentation. As a result, DCPT actuation offers unparalleled control over droplet position and speed in DMF devices.

Universal enthalpy-entropy compensation rule for the deformation of metallic glasses

“…One of the key challenges in droplet applications is how to effectively control droplets motion after their generation in microfluidic devices. Much work has been done for generation, splitting, sorting, fusion and traffic control of droplets (Thorsen et al 2001;Anna et al 2003;Murran and Abstract A theoretical model is derived mathematically for the encoding and controlling of the navigating of two droplet trains in a microfluidic network with a loop-like structure. The model reveals the relationship between the new outlet droplet train's arrangement information (output signals) and the parameters including the two droplet trains' input signals (droplet intervals), tuning flow rates, etc.…”

Electrowetting on dielectric device with crescent electrodes for reliable and low-voltage droplet manipulation

“…When performing the numerical simulation, the droplet can be approximated as a dielectric. 19,21,22 According to the law of conservation of charge and Laplace's equation …”

A dielectrophoresis microjet for on-chip technologies

“…At the core of such systems is the need for controlled uid actuation, and many onchip devices have emerged for effective uni-directional uid control in both continuous channel-based microuidic systems and discrete microdroplet-based systems. Discrete microdroplet-based systems, in particular, have demonstrated uid control with especially low reagent volumes and rapid handling, with the incorporated uni-directional uid actuation being driven by electrowetting, 9 optoelectrowetting, 10 or pressure. 11 In this work, dielectrophoresis (DEP) is investigated for on-chip operation with controlled microdroplet actuation.…”