“…N -Benzylation of 1 H -pyrazolo[3,4- b ]pyridine [ 33 ]: 1 H -pyrazolo[3,4- b ]pyridine (1 g, 8.39 mmol, 1.00 equivalent) was dissolved in acetone (10 mL) at 0 °C in a 50 mL flask, along with KOH (1.41 g, 25.19 mmol, 3.00 equivalent). After few minutes of stirring, benzyl chloride (1.59 g, 12.59 mmol, 1.50 equivalent) was added dropwise.…”