Abstract:Hepatitis C (HCV) is a widespread health issue, which can lead to hepatic cirrhosis, liver failure, and liver cancer. Nearly 2% of the world's population or > 185 million people are chronically infected with HCV; the management of HCV and the rate of sustained virological response (SVR) were significantly assisted by direct-acting antiviral medications. Since 2014, the FDA has approved using the most potent direct-acting antiviral drug (DAA) combinations. The majority of DAAs can affect cytochrome P450 (CYP) e… Show more
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