We systematically investigate the properties of three-dimensional dipolar binary Bose mixture at low temperatures. A set of coupled self-consistent equations of motion are derived for the two condensates. In the homogeneous case, useful analytical formulas for the condensate depletion, the anomalous density, the ground-state energy, and the equation of state are obtained. The theory is extended to the inhomogeneous case and the importance of the inhomogeneity is highlighted. Our results open up a new avenue for studying dipolar mixture droplets. Impacts of the dipoledipole interaction on the stability, density profiles, and the size of the self-bound droplet are deeply discussed. The finite-temperature behavior of such a state is also examined.