Diphenyl-2-Pyridylphosphine Based Palladium Catalysts for the Suzuki- Miyaura Reactions in Environment Friendly Solvents

Tairai, Archana; Shahnaz, Nasifa; Sarmah, Chandan; Das, Pankaj

doi:10.2174/157017812802139690

Cited by 2 publications

(1 citation statement)

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“…[7][8][9][10] Recently, relatively non-toxic gold nanoparticles (AuNPs) have drawn much attention due to their tunable reactivity, selectivity, and recyclability in challenging homo-and cross-coupling reactions, which could serve as an alternative for potentially toxic metalbased (e. g., Pd) catalysts. [2,9,[11][12][13][14] Even after developing these catalytically active AuNPs, finding reaction condition parame-ters that can provide the enhanced reactivity and selectivity of target molecules in mild and green environments can help to establish practical synthetic systems for the preparation of nontoxic products including food preservatives, medicines, and pharmaceutical intermediates. [3,[15][16][17] Among many reaction factors in CÀ C bond forming reactions using metal NP-based catalysts, the solvent and base are two main components, which could be additionally controlled to improve overall reaction yields.…”

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confidence: 99%

Experimental Selection of Bases for Colloidal Gold‐Polymer Composite Catalyst in Homocoupling Reactions

et al. 2022

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This work describes the empirical screening of base types and amounts on the catalytic property of gold‐polymer composite particles in the aerobic homocoupling of arylboronic acid. As these particles notably improve the yields of biaryl in the presence of bases, various bases and their amounts are systematically tested to experimentally identify an ideal base that can provide high reactivity and recyclability of the composite particles in mild and green conditions. Interestingly, the following conditions ‐ soluble strong bases at sub‐stoichiometric quantities (0.5 eq.) and insoluble weak bases at excess amounts (3.0 eq.) in EtOH ‐ significantly enhance the catalytic activities of the composite particles. Upon screening two ideal bases, overall catalytic properties of the composite particles including reaction rate at three different temperatures, activation energy (51–52 kJ/mole), and recyclability (7 cycles) were compared. Understanding the effect of bases and fine‐tuning reaction conditions can potentially improve overall reactivity and recyclability of the composite particles as a green quasi‐homogenous catalyst.

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