Diphenciprone as a therapeutic alternative to exuberant periungual warts

Souza, Bruno de Castro e; Ribeiro, Caroline Paias; Swiczar, Bethânia Cabral Cavalli; Pires, Mário Cézar

doi:10.1590/abd1806-4841.20187200

Cited by 4 publications

(3 citation statements)

References 5 publications

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“…Compared to common warts, PW grows in a special location and tends to spread under the nails, making them hard to treat, with a high recurrence rate. 1,2 In this case, the 6-year-old child was diagnosed with refractory PWs based on clinical manifestations and had tried many treatments on PWs but with no effect and even worsened, manifested by an increased number of warts, blisters, and exudation at the lesions. This patient did not respond well to conventional treatments and had a large number of warts, so we tried hyperthermia.…”

Section: Discussionmentioning

confidence: 99%

“…Compared to common warts, PW grows in a special location and tends to spread under the nails, making them hard to treat, with a high recurrence rate. 1 , 2 …”

Section: Discussionmentioning

confidence: 99%

“…Periungual wart (PW) is a type of verruca vulgaris that grows in special regions, including nearby or underlying the nails, making it more challenging to treat. 1 Traditional treatments for PW include cryotherapy, salicylic acid therapy, photodynamic therapy, antiviral drugs, and herbal treatments. 2 However, these treatments have certain disadvantages, such as cryotherapy and photodynamic therapy, which can produce great pain, and oral medications that have certain side effects.…”

Section: Introductionmentioning

confidence: 99%

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Successful Treatment in a Child with Refractory Periungual Warts by Local Hyperthermia: A Case Report

Du¹,

Cao²,

Zhu³

et al. 2022

CCID

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Periungual wart is a kind of verruca vulgaris that occurs alongside or underlying the nails, which is challenging to treat and prone to recurrence, seriously affecting the quality of patients’ life. We report a 6-year-old boy with periungual warts who had experienced various treatments with no improvement and even worsening. Therefore, we tried to treat the patient with local hyperthermia which uses a patented device that has an infrared emission source. The heat generated by infrared rays acts on the local skin surface. The mechanism of this therapy may be to establish a specific immune response against human papillomavirus-infected tissues, thereby facilitating the clearance of human papillomavirus at irradiated and non-irradiated sites. Local hyperthermia has the advantages of non-contact, safety, noninvasive, less pain, and so on. After 5 treatments, the irradiated periungual warts completely cleared after 2 weeks. The unirradiated sites were almost cured after 7 weeks. This case suggests that local thermotherapy has shown great advantages in the treatment of these refractory periungual warts and offers a new and effective therapy in patients with periungual warts.

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Section: Discussionmentioning

confidence: 99%

“…Compared to common warts, PW grows in a special location and tends to spread under the nails, making them hard to treat, with a high recurrence rate. 1 , 2 …”

Section: Discussionmentioning

confidence: 99%