Dinoflagellates Important Marine Producers of Natural Bio-Compounds with High Biotechnological and Pharmacological Potential

Ferrara, Lydia

doi:10.17756/jfcn.2020-095

Cited by 1 publication

(1 citation statement)

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“…They are mostly recognized for their negative impact resulting in harmful algal bloom (HAB) [4]. Though most of the studies have been devoted to elucidating dinoflagellate toxins owing to illnesses such as ciguatera poisoning, paralytic shellfish poisoning, and neurotoxic shellfish poisoning [5][6][7], they also possess unique bio-toxins and biologically active substances [8]. Hence, dinoflagellates are likely candidates in the development of new efficient antimicrobial drugs, especially given the emergence of multi-drug-resistant bacteria.…”

Section: Introductionmentioning

confidence: 99%

Ribosomal DNA Sequence-Based Taxonomy and Antimicrobial Activity of Prorocentrum spp. (Dinophyceae) from Mauritius Coastal Waters, South-West Indian Ocean

et al. 2023

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Microalgae are unicellular organisms and commonly present in the euphotic zone of marine ecosystems. From the western coast of Mauritius, three strains of Prorocentrum species were isolated from macrophytes and cultured under standard laboratory conditions. Morphologies were examined by light, fluorescence, and scanning electron microscopy, and phylogenetic analyses were based on partial large subunit LSU rDNA (D1-D2) and ITS1-5.8S-ITS2 (ITS) regions. Three Prorocentrum species, including the P. fukuyoi complex, P. rhathymum, and P. lima complex, were identified. The antimicrobial activities were assayed against potential human pathogenic bacterial strains. The highest zone of inhibition was recorded for intracellular and extracellular protein extracts of Prorocentrum rhathymum against Vibrio parahaemolyticus. The polysaccharide extracts of the Prorocentrum fukuyoi complex had a higher zone of inhibition (24 ± 0.4 mm) against MRSA at a minimum concentration of 0.625 μg/mL. The extracts from the three Prorocentrum species had different levels of activity against the pathogens used, and this can be of scientific interest in the search for antibiotics from natural marine sources.

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