Diminished capacity to make treatment decision for COVID-19 vaccination in schizophrenia

Raffard, Stéphane; Bayard, Sophie; Eisenblaetter, Margot; Tattard, Philippe; Attal, J.; Laraki, Yasmine; Capdevielle, Delphine

doi:10.1007/s00406-022-01413-9

Cited by 6 publications

(7 citation statements)

References 18 publications

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“…Recently and within the context of the COVID-19 pandemic, two large-scale studies have shown that both conspiracy beliefs and persecutory ideas, two psychological features that are highly present in individuals with schizophrenia, were positively associated with COVID-19 vaccine hesitancy and resistance in the general population [15,16]. Finally, our research team recently showed that impaired competence to consent to a COVID-19 vaccine was associated with lower vaccination rates in people with schizophrenia [17].…”

Section: Introductionmentioning

confidence: 86%

Attitudes towards Vaccines, Intent to Vaccinate and the Relationship with COVID-19 Vaccination Rates in Individuals with Schizophrenia

et al. 2022

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Schizophrenia patients are at high risk of developing severe COVID-19 outcomes but recent evidence suggests that they are under-vaccinated. This study explored the role of potential attitudinal barriers by comparing schizophrenia patients with participants from the general population regarding COVID-19 vaccination rates, general attitudes towards vaccines, and willingness to take a COVID-19 vaccine. We conducted a cross-sectional study between April 2021 and October 2021. A total of 100 people with schizophrenia and 72 nonclinical controls were recruited. In our study, individuals with schizophrenia were under-vaccinated, despite similar general attitudes towards vaccination and higher willingness to be vaccinated against COVID-19 compared to nonclinical participants. In patients, negative attitudes toward vaccines were related to higher levels of negative psychotic symptoms and higher levels of paranoid ideation. As a whole, participants with more negative attitudes towards vaccines were less likely to be vaccinated against COVID-19 and had lower levels of trust in institutions. Vaccine hesitancy does not appear to be a major barrier for COVID-19 vaccine uptake amongst people with schizophrenia. This study suggests that disparities in COVID-19 vaccination rates in schizophrenia do not seem related to attitudinal but rather structural barriers.

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Section: Introductionmentioning

confidence: 86%

Attitudes towards Vaccines, Intent to Vaccinate and the Relationship with COVID-19 Vaccination Rates in Individuals with Schizophrenia

et al. 2022

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“…Of potential note here, patients believing COVID-19 conspiracy theories may be more prone to contracting the virus, which may itself be a risk factor for developing psychosis [ 64 ]. Interestingly, a recent study by Raffard et al demonstrated that patients with schizophrenia have diminished capacity to consent to COVID-19 vaccination [ 65 ].…”

Section: Discussionmentioning

confidence: 99%

Approaching differential diagnosis and decisional capacity assessment in the context of COVID-19 conspiracy beliefs: A narrative review and clinical discussion

Serdenes¹,

Arana²,

Karasin³

et al. 2023

General Hospital Psychiatry

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“…Unwillingness to vaccine has been associated with greater psychiatric symptoms in patients with schizophrenia: symptomatic patients with schizophrenia frequently are suspicious of the Government for wanting to vaccinate people and develop paranoid delusions around the vaccination itself and the process [55][56][57]. However, this suspicion was not limited to patients with psychotic disorders and younger age, lower education and economic status, right-wing and conservative ideology have been associated with increased belief in misinformation [58].…”

Section: Vaccination Policies Unwillingness To Vaccine and Rates Of V...mentioning

confidence: 99%

Lessons from the coronavirus disease 2019 pandemic in schizophrenia: a review

Fond

Boyer

2023

Current Opinion in Psychiatry

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Purpose of reviewMultiple countries have reported increased COVID-19 mortality in patients with schizophrenia. The purpose of this review was to synthetize the consequences of the pandemic on patients with schizophrenia including vaccination data.Recent findingsWe have synthetized data on the increased risk of infection and increased mortality, the impact of the pandemic and lockdowns on psychiatric care, vaccination policies, unwillingness to vaccine in patients and the rates of vaccination.SummarySchizophrenia has been confirmed at increased risk of both COVID-19 infection and developing a severe/lethal form of the infection. Patients with schizophrenia should, therefore, be prioritized for vaccination whenever possible and should be prioritized for psychiatric and somatic care access. Psychotic symptomatology may be a barrier to vaccination in some patients, and heterogenous vaccination rates were identified in national databases. The COVID-19 pandemic has been also a unique opportunity to develop telehealth. A mixed face-to-face and distance model should be encouraged, whenever possible, to improve the experience of patients, relatives and healthcare professionals. No major change of long-acting antipsychotics has been reported in most countries, and there was no consistent evidence for clozapine prescription to increase the risk of COVID-19 infection or severe outcomes.

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Diminished capacity to make treatment decision for COVID-19 vaccination in schizophrenia

Cited by 6 publications

References 18 publications

Attitudes towards Vaccines, Intent to Vaccinate and the Relationship with COVID-19 Vaccination Rates in Individuals with Schizophrenia

Attitudes towards Vaccines, Intent to Vaccinate and the Relationship with COVID-19 Vaccination Rates in Individuals with Schizophrenia

Approaching differential diagnosis and decisional capacity assessment in the context of COVID-19 conspiracy beliefs: A narrative review and clinical discussion

Lessons from the coronavirus disease 2019 pandemic in schizophrenia: a review

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