Diminished baroreflex function following ovariectomy is a consequence of the reduced excitability of a sex specific population of low threshold myelinated baroreceptor afferents in the rat
Abstract:Concomitant with menopause there is a significant reduction in the capacity of the baroreflex (BRx). Loss of so‐called sex hormones is but one factor. Our previous in situ BRx studies have validated and quantified the contribution of a sex specific subpopulation of low‐threshold myelinated aortic baroreceptor afferents (Ah‐type) in eliciting depressor dynamics not observed in male rats. Ovariectomy greatly reduces the excitability of these Ah‐type afferents while the excitability of low threshold myelinated A‐… Show more
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