“…6 Calcium channel blockers have also been used to treat chronic malignancyeassociated perineal pressure like pain and tenesmus. 7 Symptoms associated with lumbosacral plexopathy, an unrecognized consequence of treatment of anal cancer treatment with chemotherapy and radiation, are usually treated with opioids, steroid suppositories, and lidocaine ointments. 8 Anal pain from low-lying rectal cancer, in patients who received preoperative chemoradiotherapy and underwent intersphincteric resection technique, was adequately controlled with opioids such as oxycodone.…”