Dilemmas in the diagnosis and treatment of intracranial tuberculomas

Ramachandran, Rajeswari; Muniyandi, Malaisamy; Iyer, Vijay; Sripriya, T.; Priya, B.; Govindarajan, T.G.

doi:10.1016/j.jns.2017.08.3258

Cited by 34 publications

(31 citation statements)

References 18 publications

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Section: Discussionmentioning

confidence: 99%

“…Intracranial tuberculomas are still common in developing countries [5]. They usually result from hematogenous spread of the mycobacterium tuberculosis to the leptomeninges and brain parenchyma from pulmonary tuberculosis [5]. En plaque Tuberculoma is a rare manifestation, with dural insertion, that appears as a solid mass that morphologically resembles a meningioma plaque or meningeal metastases [6] They are usually seen in young adults and the pediatric population where they frequently occur in the infratentorial components as opposed to our case [6].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Pachymeningeal en Plaque Tuberculoma in Children: A Case Report

Berete¹,

Bah²,

Diawara³

et al. 2020

OJMN

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Pachymeningeal en plaque tuberculoma is a rare manifestation of tuberculosis and has a poor prognosis if not diagnosed early and treated adequately. The aim of the present paper is to collect the reported clinical and radiological signs in the literature and compare it with a personal observation to evaluate the possibility of a presumptive diagnosis. A 4-year-old boy presented at the pediatric emergency department with 7 days history of severe headache, vomiting blurred vision and had one partial seizure. His neurologic examination was notable for decreased visual acuity with bilateral papilledema and intact extra-ocular muscles. His neck was rigid. Neuroimaging revealed a multifocal dural-based mass on the fronto-parietal convexity with dense heterogeneous contrast enhancement and hydrocephalus. He has undergone a Ventriculoperitoneal shunt and surgical excision of the mass the next day. Outcome was favorable with antituberculosis therapy and corticosteroids. The clinical presentation and outcome were similar to the reported cases in the literature.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Pachymeningeal en Plaque Tuberculoma in Children: A Case Report

Berete¹,

Bah²,

Diawara³

et al. 2020

OJMN

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“…Central nervous system (CNS) TB is associated with a high mortality and morbidity [1]. Tuberculous myelopathy is a rare form of neurological TB [2].…”

Section: Discussionmentioning

confidence: 99%

A rare neurological complication of tuberculosis: Transverse myelitis

Ortega-Rosales¹,

Delgado-Torres

Burneo-Rosales³

2019

IDCases

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Acute transverse myelitis is a rare inflammatory demyelinating disorder characterized by relatively acute onset of motor, sensory, and autonomic dysfunction. Mycobacterium tuberculosis is a very rare cause of transverse myelitis. We present a patient with tuberculosis presenting with meningitis and transverse myelitis who had marked clinical improvement and neurologic recovery after treatment of tuberculosis and intravenous steroid pulses.

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“…El tuberculoma puede presentarse como un granuloma caseificante en cualquier parte del sistema nervioso central, como lesión única o múltiple, acompañado de un anillo de realce del contraste que es inversamente proporcional al tiempo de evolución de la enfermedad 9,19 . Existe una variante del granuloma no caseificante que presenta un realce homogéneo con calcificación central, similar a la neurocisticercosis (signo de tiro al blanco) 20,21 que es detectado por la TAC con una sensibilidad cercana al 100% y una especificidad y VPN (31%) muy bajos 22 . En la RM contrastada, se presentan las dos variantes: el tuberculoma caseificante característicamente iso o hipointenso en T1 y T2 con un anillo iso o hiperintenso en T2 y el no caseificante que es hiperintenso en T2 y ligeramente hipointenso en T1.…”

Section: Discussionunclassified

Tuberculoma intracerebral en gestante inmunocompetente

Cajiao¹

2018

Rev Fac Cien Med (Quito)

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la tuberculosis causada por la bacteria Mycobacterium tuberculosis, se encuentra entre las 10 primeras causas de mortalidad a nivel mundial; la presentación extrapulmonar se produce por siembra vía hematógena o linfática desde un foco primario, correspondiendo a la afectación de sistema nervioso central el 5% de infecciones por TB y se presenta con menor frecuencia en personas inmunocompetentes. Las formas de tuberculosis de SNC son meningitis, tuberculosis espinal y tuberculomas que corresponden al 1% de infecciones por TB. El tratamiento se basa en la terapia antifímica, reservando el manejo neuroquirúrgico para puntuales indicaciones como deterioro neurológico, hidrocefalia o mala respuesta al tratamiento farmacológico.

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Dilemmas in the diagnosis and treatment of intracranial tuberculomas

Cited by 34 publications

References 18 publications

Pachymeningeal en Plaque Tuberculoma in Children: A Case Report

Pachymeningeal en Plaque Tuberculoma in Children: A Case Report

A rare neurological complication of tuberculosis: Transverse myelitis

Tuberculoma intracerebral en gestante inmunocompetente

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