Abstract:Protein fibrillation is believed to play an important role in the pathology and development of several human diseases, such as Alzheimer's disease, Parkinson's disease and type 2 diabetes. Carbon dots (CDs), as a new type of nanoparticle have recently been extensively studied for potential biological applications, but their effects on protein fibrillation remain unexplored. In reality, any application in biological systems will inevitably have "contact" between proteins and CDs. In this study, human insulin wa… Show more
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