Digitalizing the TIM-1 Model using Computational Approaches–Part One: TIM-1 Data Explorer
Inese Sarcevica,
Bart Hens,
Irena Tomaszewska
et al.
Abstract:The TIM-1 gastrointestinal model is one of the most advanced in vitro systems currently available for biorelevant dissolution testing. This technology, the initial version of which was developed nearly 30 years ago and has been subject to a number of significant updates over this period, simulates the dynamic environment of the human gastrointestinal tract, including pH, transfer times, secretion of bile, enzymes, and electrolytes. In the pharmaceutical industry, the TIM-1 system is used to support drug produc… Show more
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