Digital tomosynthesis and ground glass nodules: Optimization of acquisition protocol. A phantom study

Baratella, Elisa; Bozzato, Alessandro Marco; Marrocchio, Cristina; Natali, C.; Giusto, Anna Di; Quaia, Emilio; Cova, Maria Assunta

doi:10.1016/j.radi.2020.11.019

Cited by 3 publications

(1 citation statement)

References 27 publications

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“…An anthropomorphic thoracic phantom (LUNGMAN, Kyoto Kagaku, Kyoto, Japan) was prepared via insertion of two homogeneous spherical simulated ground glass opacity (GGO) lung nodules. GGO nodules are not always indicative of cancer and can represent benign conditions such as organizing pneumonia, inflammation, focal fibrosis, and bleeding 10 , and are therefore an appropriate target for this evaluation. An 8mm nodule of +100 HU and 10mm nodule of -630 HU were placed within the lung.…”

Section: Phantom Imagingmentioning

confidence: 99%

X-ray source array optimization for mobile chest tomosynthesis

Inscoe,

Billingsley,

Zhao

et al. 2024

Medical Imaging 2024: Physics of Medical Imaging

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Purpose: Portable chest x-ray (PCXR) is commonly employed in intensive care units (ICU). CXR provides valuable information but is hindered by structural overlap. Digital chest tomosynthesis (DCT) removes overlap, yielding quasithree-dimensional images. Spatially distributed x-ray source arrays eliminate complex mechanical motion and are wellsuited for mobile systems. The purpose of this study is to design and optimize a compact and portable DCT system employing a linear field emission x-ray source array in lieu of a conventional moving source, balancing image quality with size and clinical practicality.Methods: A prototype stationary DCT system was used to test a variety of system configurations. Tomosynthesis scans of an anthropomorphic phantom were performed repeatedly to generate an image ensemble. Subsets were selected for reconstruction to investigate the impact of spatial distribution on image quality. Reconstruction slice images were evaluated by visualization of simulated lung nodules and presence of artifact to determine the optimal source configuration.Results: Reconstruction slice images demonstrated out-of-plane artifact in configurations with low projection image density. Narrow angular span compromised the visualization of structures and low contrast features. Of the evaluated configurations, one was determined to best balance image quality with physical constraints, utilizing 15 projections covering an angular span of 23 degrees.Conclusion: Bedside 3D imaging is achievable by use of x-ray source arrays. A configuration was determined that generates good image quality in a size conducive to design of a mobile tomosynthesis system. Such a system should provide increased clinical utility compared to 2D radiography in the ICU.

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Section: Phantom Imagingmentioning

confidence: 99%

X-ray source array optimization for mobile chest tomosynthesis

Inscoe,

Billingsley,

Zhao

et al. 2024

Medical Imaging 2024: Physics of Medical Imaging

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Patient-specific scatter-corrected digital chest tomosynthesis in human subjects

Inscoe

Billingsley

Puett

et al. 2022

Medical Imaging 2022: Physics of Medical Imaging

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Next-generation digital chest tomosynthesis

Gange,

Ku,

Gosangi

et al. 2024

JCIS

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The objective of this study was to demonstrate the performance characteristics and potential utility of a novel tomosynthesis device as applied to imaging the chest, specifically relating to lung nodules. The imaging characteristics and quality of a novel digital tomosynthesis prototype system was assessed by scanning, a healthy volunteer, and an andromorphic lung phantom with different configurations of simulated pulmonary nodules. The adequacy of nodule detection on the phantoms was rated by chest radiologists using a standardized scale. Results from using this tomosynthesis device demonstrate in plane resolution of 16lp/cm, with estimated effective radiation doses of 90% less than low dose CT. Nodule detection was adequate across various anatomic locations on a phantom. These proof-of-concept tests showed this novel tomosynthesis device can detect lung nodules with low radiation dose to the patient. This technique has potential as an alternative to low dose chest CT for lung nodule screening and tracking.

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Digital tomosynthesis and ground glass nodules: Optimization of acquisition protocol. A phantom study

Cited by 3 publications

References 27 publications

X-ray source array optimization for mobile chest tomosynthesis

X-ray source array optimization for mobile chest tomosynthesis

Patient-specific scatter-corrected digital chest tomosynthesis in human subjects

Next-generation digital chest tomosynthesis

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