Digital signal processor control of scanned probe microscopes

Baselt, David R.; Clark, Steven M.; Youngquist, M. G.; Spence, Charles; Baldeschwieler, John D.

doi:10.1063/1.1144462

Cited by 34 publications

(15 citation statements)

References 16 publications

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“…Recent studies have shown that elastic properties of cells can be detected with the AFM (Hoh and Schoenenberger, 1994). Imaging of elastic properties with the AFM is possible using force modulation (Radmacher et al, 1993;Baselt et al, 1993), which has been applied to platelets (Radmacher et al, 1992) and magnetotactic bacteria . Quantitative analysis of the elastic or other sample properties can be obtained with the AFM by taking force curves, as pointed out earlier (Burnham and Colton, 1989;Weisenhom et al, 1989Weisenhom et al, , 1992.…”

Section: Introductionmentioning

confidence: 99%

Measuring the viscoelastic properties of human platelets with the atomic force microscope

Radmacher

Fritz

Kacher

et al. 1996

Biophysical Journal

767

539

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We have measured force curves as a function of the lateral position on top of human platelets with the atomic force microscope. These force curves show the indentation of the cell as the tip loads the sample. By analyzing these force curves we were able to determine the elastic modulus of the platelet with a lateral resolution of approximately 100 nm. The elastic moduli were in a range of 1-50 kPa measured in the frequency range of 1-50 Hz. Loading forces could be controlled with a resolution of 80 pN and indentations of the platelet could be determined with a resolution of 20 nm.

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Section: Introductionmentioning

confidence: 99%

Measuring the viscoelastic properties of human platelets with the atomic force microscope

Radmacher

Fritz

Kacher

et al. 1996

Biophysical Journal

767

539

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“…Obviously the original analog control circuits (Binnig et al , 1982;Munoz et al , 1998) fail to meet this requirement. The digital control methods popular nowadays are usually composed of a computer and digital circuits such as a digital signal processor (DSP) (Wong and Welland 1993;Baselt et al , 1993;Heuel et al , 1994;Barchesi et al , 1997;Scheuring et al , 1998;Boudreau et al , 2002). The digital circuits perform the core control routine which is to a large extent fixed by the original designer, and the modifications require professional knowledge and abundant experience.…”

Section: Introductionmentioning

confidence: 99%

Soft Control of Scanning Probe Microscope with High Flexibility

et al. 2007

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Most commercial scanning probe microscopes have multiple embedded digital microprocessors and utilize complex software for system control, which is not easily obtained or modified by researchers wishing to perform novel and special applications. In this paper, we present a simple and flexible control solution that just depends on software running on a single-processor personal computer with real-time Linux operating system to carry out all the control tasks including negative feedback, tip moving, data processing and user interface. In this way, we fully exploit the potential of a personal computer in calculating and programming, enabling us to manipulate the scanning probe as required without any special digital control circuits and related technical know-how. This solution has been successfully applied to a homemade ultrahigh vacuum scanning tunneling microscope and a multiprobe scanning tunneling microscope.

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“…6,7 This system uses an optical lever detection scheme to monitor the cantilever displacement. In order to determine the frequency characteristics of the cantilever motion, the output of the photodiode preamplifier was connected directly to a HP spectrum analyzer.…”

Section: Methodsmentioning

confidence: 99%

Noise reduction in atomic force microscopy: Resonance contact mode

O'Connor

Gamble

Eby

et al. 1996

Review of Scientific Instruments

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Noise reduction has been accomplished in atomic force microscopy by applying a high frequency, low amplitude vibration to the cantilever while it is in contact with a surface. The applied excitation ͑Ͼ200 kHz; ϳ1 nm͒ is acoustically coupled to the tip and dampens the resonance Q factors of the system. The applied frequency is well above the bandwidth of the acquisition system ͑50 kHz͒. We call this mode ''resonance contact'' mode. The nonlinear behavior of the tip-sample interaction allows the high frequency excitation to effectively broaden the frequency response of the system resonances.

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Digital signal processor control of scanned probe microscopes

Cited by 34 publications

References 16 publications

Measuring the viscoelastic properties of human platelets with the atomic force microscope

Measuring the viscoelastic properties of human platelets with the atomic force microscope

Soft Control of Scanning Probe Microscope with High Flexibility

Noise reduction in atomic force microscopy: Resonance contact mode

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