Digital Photoinduced Topographical Microsculpting of Hydrogels
Maaike Bril,
Mirko D'Urso,
Mario Prejanò
et al.
Abstract:Hydrogels are soft materials widely used as a substrate or matrix for cell culture to mimic the physicochemical, structural, and mechanical properties of the cell's native microenvironment. Recently, a growing body of evidence has shown that substrate topography is a key determinant of cell behavior. These studies, however, mostly rely on the use of hard elastomeric materials, particularly as introducing topography in soft hydrogels is technically challenging, labor intensive, and often does not provide a flex… Show more
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