Digital image analysis for biothreat detection via rapid centrifugal microfluidic orthogonal flow immunocapture

Abstract

We report centrifugally-driven, orthogonal flow immunocapture (cOFI) of Zaire Ebola virus-like particles with an accompanying rich, colorimetric image analysis approach that does not require commercial ‘strip readers’ or custom analysis algorithms.

Advancements and future directions in cardiac biomarker detection using lateral flow assays

“…), rendering in a rapid color change in the test line if the target analyte is present. Due to those inherent characteristics, LFA devices have been gaining popularity as efficient point-of-care diagnostic tools, facilitating easy accessibility of the results to untrained users as extensively demonstrated in various applications, such as pregnancy tests, 18 pathogen detection, 19,20 and more recently in the field of COVID-19 diagnostics. 21–25…”