Digital Breast Tomosynthesis in the Diagnostic Environment: A Subjective Side-by-Side Review

Hakim, Christiane M.; Chough, Denise M.; Ganott, Marie A.; Sumkin, Jules H.; Zuley, Margarita L.; Gur, David

doi:10.2214/ajr.09.3244

Cited by 117 publications

(75 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Similar results have been reported in previous studies on Western populations (Andersson et al, 2008;Hakim et al, 2010;Helvie, 2010;Teertstra et al, 2010;Williams et al, 2010;Vecchio et al, 2011;Michell et al, 2012;Alakhras et al, 2013;Houssami et al, 2013;Skaane et al, 2013;Zuley et al, 2013). Our study showed that 3DBT improved the diagnosis accuracy compared to 2DMMG in Japanese female population and 3DBT is a novel technique that may provide a breakthrough in solving the difficulties of diagnosis caused by parenchyma overlap in 2DMMG.…”

Section: Discussionsupporting

confidence: 90%

“…Nowadays, advancements in digital detector technology have enabled its application in clinical practice (Andersson et al, 2008;Hakim et al, 2010;Helvie, 2010;Teertstra et al, 2010;Williams et al, 2010;Vecchio et al, 2011). In 3D digital mammography tomosynthesis (3DBT), tomographic images are reconstructed from multiple projections acquired from different angles.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Role of Breast Tomosynthesis in Diagnosis of Breast Cancer for Japanese Women

Takamoto¹,

Tsunoda²,

Kikuchi³

et al. 2013

Asian Pacific Journal of Cancer Prevention

View full text Add to dashboard Cite

Introduction: Mammography is the most basic modality in breast cancer imaging. However, the overlap of breast tissue depicted on conventional two-dimensional mammography (2DMMG) may create significant obstacles to detecting abnormalities, especially in dense or heterogeneously dense breasts. In three-dimensional digital breast tomosynthesis (3DBT), tomographic images of the breast are reconstructed from multiple projections acquired at different angles. It has reported that this technology allows the generation of 3D data, therefore overcoming the limitations of conventional 2DMMG for Western women. We assessed the detectability of lesions by conventional 2DMMG and 3DBT in diagnosis of breast cancer for Japanese women. Methods: The subjects were 195 breasts of 99 patients (median age of 48 years, range 34~82 years) that had been pathologically diagnosed with breast cancer from December 20, 2010 through March 31, 2011. Both conventional 2DMMG and 3DBT imaging were performed for all patients. Detectability of lesions was assessed based on differences in category class. Results: Of the affected breasts, 77 (75.5%) had lesions assigned to the same categories by 2DMMG and 3DBT. For 24 (23.5%) lesions, the category increased in 3DBT indicating improvement in diagnostic performance compared to 2DMMG. 3DBT improved diagnostic sensitivity for patients with mass, focal asymmetric density (FAD), and architectural distortion. However, 3DBT was not statistically superior in diagnosis of the presence or absence of calcification. Conclusions: In this study, 3DBT was superior in diagnosing lesions in form of mass, FAD, and/or architectural distortion. 3DBT is a novel technique that may provide a breakthrough in solving the difficulties of diagnosis caused by parenchyma overlap for Japanese women.

show abstract

Section: Discussionsupporting

confidence: 90%

Section: Introductionmentioning

confidence: 99%

Role of Breast Tomosynthesis in Diagnosis of Breast Cancer for Japanese Women

Takamoto¹,

Tsunoda²,

Kikuchi³

et al. 2013

Asian Pacific Journal of Cancer Prevention

View full text Add to dashboard Cite

show abstract

“…Although this study was not designed to assess DBT in the diagnostic and assessment setting, improved visualisation of benign and malignant features using DBT could reduce the need for additional ultrasound, MRI or supplemental mammographic imaging. [39][40][41][42] The screening population would also benefit if some of the anxiety and stress associated with breast screening from unnecessary recalls and additional testing could be reduced.…”

Section: Resultsmentioning

confidence: 99%

“…[28][29][30] Improved lesion visibility, size and classification compared with standard film or digital mammography have been reported [31][32][33][34][35][36][37][38] and the possibility that DBT could reduce the need for additional mammographic views at least for non-calcified lesions [39][40][41][42] has been suggested. There are mixed reports of the sensitivity of DBT for the detection of microcalcifications 32,[43][44][45][46][47][48][49][50][51] that may be partly as a result of the different techniques used for image reconstruction and the need to combine image slices into thicker slabs for optimal visualisation of microcalcification clusters.…”

Section: Diagnostic Accuracymentioning

confidence: 99%

The TOMMY trial: a comparison of TOMosynthesis with digital MammographY in the UK NHS Breast Screening Programme – a multicentre retrospective reading study comparing the diagnostic performance of digital breast tomosynthesis and digital mammography with digital mammography alone

Gilbert

Tucker

Gillan

et al. 2015

Health Technology Assessment

155

View full text Add to dashboard Cite

The TOMMY trial: a comparison of TOMosynthesis with digital MammographY in the UK NHS Breast Screening Programme -a multicentre retrospective reading study comparing the diagnostic performance of digital breast tomosynthesis and digital mammography with digital mammography alone This journal is a member of and subscribes to the principles of the Committee on Publication Ethics (COPE) (www.publicationethics.org/).Editorial contact: nihredit@southampton.ac.ukThe full HTA archive is freely available to view online at www.journalslibrary.nihr.ac.uk/hta. Print-on-demand copies can be purchased from the report pages of the NIHR Journals Library website: www.journalslibrary.nihr.ac.uk Criteria for inclusion in the Health Technology Assessment journalReports are published in Health Technology Assessment (HTA) if (1) they have resulted from work for the HTA programme, and (2) they are of a sufficiently high scientific quality as assessed by the reviewers and editors.Reviews in Health Technology Assessment are termed 'systematic' when the account of the search appraisal and synthesis methods (to minimise biases and random errors) would, in theory, permit the replication of the review by others. HTA programmeThe HTA programme, part of the National Institute for Health Research (NIHR), was set up in 1993. It produces high-quality research information on the effectiveness, costs and broader impact of health technologies for those who use, manage and provide care in the NHS. 'Health technologies' are broadly defined as all interventions used to promote health, prevent and treat disease, and improve rehabilitation and long-term care.The journal is indexed in NHS Evidence via its abstracts included in MEDLINE and its Technology Assessment Reports inform National Institute for Health and Care Excellence (NICE) guidance. HTA research is also an important source of evidence for National Screening Committee (NSC) policy decisions.For more information about the HTA programme please visit the website: http://www.nets.nihr.ac.uk/programmes/hta This reportThe research reported in this issue of the journal was funded by the HTA programme as project number 09/22/182. The contractual start date was in December 2010. The draft report began editorial review in February 2014 and was accepted for publication in August 2014. The authors have been wholly responsible for all data collection, analysis and interpretation, and for writing up their work. The HTA editors and publisher have tried to ensure the accuracy of the authors' report and would like to thank the reviewers for their constructive comments on the draft document. However, they do not accept liability for damages or losses arising from material published in this report. Background: Digital breast tomosynthesis (DBT) is a three-dimensional mammography technique with the potential to improve accuracy by improving differentiation between malignant and non-malignant lesions.

show abstract

“…While the percentage of cases with malignancies are included in the table, a large study (123) investigating abnormality prevalence rates ranging from 2% to 29% in various groups of readers (radiologists, fellows, residents) showed that the "prevalence effect" had negligible contribution in ROC studies. Pilot studies and interim reader studies with less than 100 subjects that preceded some of the studies discussed above have been reported (124)(125)(126)(127)(128). Some of the studies used unilateral examinations and the information from contralateral breast was unavailable for comparison.…”

Section: Retrospective Multireader Multicase Studiesmentioning

confidence: 99%

Digital Breast Tomosynthesis: State of the Art

et al. 2015

View full text Add to dashboard Cite

This topical review on digital breast tomosynthesis (DBT) is provided with the intent of describing the state of the art in terms of technology, results from recent clinical studies, advanced applications, and ongoing efforts to develop multimodality imaging systems that include DBT. Particular emphasis is placed on clinical studies. The observations of increase in cancer detection rates, particularly for invasive cancers, and the reduction in false-positive rates with DBT in prospective trials indicate its benefit for breast cancer screening. Retrospective multireader multicase studies show either noninferiority or superiority of DBT compared with mammography. Methods to curtail radiation dose are of importance

show abstract

Digital Breast Tomosynthesis in the Diagnostic Environment: A Subjective Side-by-Side Review

Abstract: DBT may be an alternative to obtaining additional mammographic views in most but not all cases of patients with a lesion that is not solely calcifications. In a fraction of cases, the use of DBT may eliminate the need for ultrasound.

Cited by 117 publications

References 12 publications

Role of Breast Tomosynthesis in Diagnosis of Breast Cancer for Japanese Women

Role of Breast Tomosynthesis in Diagnosis of Breast Cancer for Japanese Women

The TOMMY trial: a comparison of TOMosynthesis with digital MammographY in the UK NHS Breast Screening Programme – a multicentre retrospective reading study comparing the diagnostic performance of digital breast tomosynthesis and digital mammography with digital mammography alone

Digital Breast Tomosynthesis: State of the Art

Contact Info

Product

Resources

About