Abstract:2,4-Dichlorophenoxyacetic acid (2,4-D) is a herbicide of the chlorophenoxy class and the second most widely used herbicide applied to several different crops worldwide. Environmental factors, especially those related to diet, strongly affect the risk of developing cancer of the gastrointestinal tract. There is currently no evidence to determine whether there is an association between 2,4-D exposure and gastrointestinal disorders. We evaluated the histological effect of chronic oral and inhalation exposure to 2… Show more
“…13,14 This herbicide induces ocular irritation and gastrointestinal distress, and has the potential to be hazardous to sh and other aquatic species. [15][16][17] 2,4-D was a constituent of Agent Orange, the pesticide that was extensively utilized during the Vietnam War. While 2,4-D accounted for 50% of the composition of Agent Orange, the health consequences of Agent Orange are mainly attributed to the presence of dioxin pollutants produced during its manufacturing process rather than 2,4-D itself.…”
“…13,14 This herbicide induces ocular irritation and gastrointestinal distress, and has the potential to be hazardous to sh and other aquatic species. [15][16][17] 2,4-D was a constituent of Agent Orange, the pesticide that was extensively utilized during the Vietnam War. While 2,4-D accounted for 50% of the composition of Agent Orange, the health consequences of Agent Orange are mainly attributed to the presence of dioxin pollutants produced during its manufacturing process rather than 2,4-D itself.…”
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.