Digestion of starch in a dynamic small intestinal model

Abstract

Overall, the work highlights the significance of gut motility in digestive processes and offers a powerful tool in nutritional studies that, additionally to biochemical, considers engineering aspects of digestion. The potential to modulate food digestibility and nutrient bioaccessibility by altering food formulation is indicated.

Strategic choices for in vitro food digestion methodologies enabling food digestion design

“…The small intestine is considered the major area for nutrient absorption, as it has a large external surface area of about 30 m 2 lined with villi and microvilli (Boland, 2016;Jaime-Fonseca et al, 2016). Nutrient absorption competes with the transit through the intestine, which takes between 2 and 5 hours (Boland, 2016).…”

A standardised semi-dynamic in vitro digestion method suitable for food – an international consensus

“…However, the chyme emptied from the gastric phase is digested separately in parallel. The rationale for this approach as opposed to simply passing gastric samples into a single intestinal vessel is that segmentation within the small intestine means that the content can in some senses be treated as a plug flow 97 and thus digested separately from samples emptied at other time points. The static protocol of the COST Action INFOGEST has been seen as useful for the assessment of the end values but it cannot provide data about the kinetics of nutrient digestion.…”

Protein Hydrolysates’ Absorption Characteristics in the Dynamic Small Intestine In Vivo

“…The intestine is the most important organ for food absorption. The majority (80%) of nutrient absorption occurs in the small intestine, where chyme enters from the stomach and it is further broken down into nutrients [ 7 ]. In 2010 a study on a simulated model of the small intestine was reported [ 6 ].…”

“…In the large intestine the residual food components that have not already been digested are fermented by microorganisms. Some products are absorbed and the others are egested [ 6 , 7 , 8 ]. On the other hand, the digestion and absorption of food in the human gastrointestinal tract (GIT) system is a complex process including physical, chemical and biological process, and little is known about its biological process.…”