2015
DOI: 10.1155/2015/854373
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Digestibility and Bioavailability of the Active Components ofErica australisL. Aqueous Extracts and Their Therapeutic Potential as Acetylcholinesterase Inhibitors

Abstract: Erica australis L. (Ericaceae) is used in traditional medicine to treat many free-radical related ailments. In the present work, the stability and biological activity of the plant aqueous extracts submitted to an in vitro digestive process were investigated. Chemical stability was monitored by HPLC-DAD and LC-MS/MS, while the bioactivities were evaluated through the inhibition of acetylcholinesterase (AChE) and DPPH radical scavenging activity. Both extracts, whose main components were flavonol glycosides, inh… Show more

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Cited by 5 publications
(3 citation statements)
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“…The observed decreases of 10 and 20% of the activity could be due to interference with the test reagents, which are corroborated by HPLC analysis. Our results are in accordance with those reported for Lavandula viridis L'H er (Lamiaceae) extracts (Costa et al 2014) and Erica australis L. (Ericaceae) extracts (Dias et al 2015).…”
Section: Determination Of Acetylcholinesterase Inhibitory Activitysupporting
confidence: 93%
“…The observed decreases of 10 and 20% of the activity could be due to interference with the test reagents, which are corroborated by HPLC analysis. Our results are in accordance with those reported for Lavandula viridis L'H er (Lamiaceae) extracts (Costa et al 2014) and Erica australis L. (Ericaceae) extracts (Dias et al 2015).…”
Section: Determination Of Acetylcholinesterase Inhibitory Activitysupporting
confidence: 93%
“…Erica species (Ericaceae) are used in folk medicine for their therapeutic properties including antimicrobial, antiviral, diuretic, anti-inflammatory, antinociceptive and antiulcer activities [ 21 ]. Erica arborea L. (tree heath) is an evergreen shrub or small tree, native to south-west Europe, the Mediterranean region and northern Africa.…”
Section: Introductionmentioning
confidence: 99%
“…Extracts of several medicinal plants have been reported to be effective in the inhibition of BChE and AChE [17]. Several plants from Ericaceae family have shown a very strong inhibitory activity against AChE and BChE [18].…”
Section: Introductionmentioning
confidence: 99%