Diffusion-weighted MR imaging with background body signal suppression (DWIBS) for the diagnosis of malignant and benign breast lesions

Abstract

The purpose of this study was to evaluate the efficacy of diffusion-weighted MR imaging with background body signal suppression (DWIBS) and a conventional DWI (cDWI) sequence for the detection of breast lesions. Fifty consecutive patients with suspected breast lesions underwent DWIBS and cDWI at 1.5 T. The routine protocol consisted of a short TI inversion recovery (STIR) sequence and a dynamic contrast-enhanced T1-weighted sequence. Apparent diffusion coefficient (ADC) and exponential ADC (eADC) values of the lesions were calculated. Receiver operating characteristic (ROC) analyses and qualitative evaluation of lesion detectability and conspicuity were performed. Thirty-six lesions were detected in 30 patients by using the routine protocol. DWIBS detected 34 lesions (94%) and cDWI detected 26 lesions (72%). The conspicuity of fibroadenomas was significantly (P = 0.007) better for DWIBS. ADC and eADC values of tumour were significantly different between DWIBS and cDWI. DWIBS is superior to cDWI in the visualization of malignant and benign lesions in the breast.

Breast DWI at 3 T: influence of the fat-suppression technique on image quality and diagnostic performance

“…4 Minor lipid peaks at different resonance frequencies 33 remain unsuppressed and still contribute to the final signal intensity. 34,35 Additionally, STIR seems to produce a more spatially homogeneous suppression throughout the image. Given that the acquisition parameters are very similar for both DW sequences, the differences found on the image-quality parameters can be attributed to the fat-suppression module applied.…”

Effect of gadolinium injection on diffusion-weighted imaging with background body signal suppression (DWIBS) imaging of breast lesions

“…m r i j o u r n a l . c o m DWIBS provides both qualitative and quantitative imaging with apparent diffusion coefficient (ADC) values specific for benign or malignant lesions [21].…”

“…Its reported sensitivity, specificity, diagnostic accuracy, PPV and NPV values are of 100, 82, 87, 68 and 100%, respectively [20]. The suppression of the breast adipose tissue allows to increase the detection rate of glandular lesions by using free breathing scans [20,21]. …”

Diagnostic accuracy of diffusion-weighted whole-body imaging with background body signal suppression/T2-weighted image fusion for the detection of abdominal solid cancer

“…DWIBS is used to detect cancer in organs that are not influenced by respiration, such as in the breast (5). The existing literature regarding DWIBS mainly involves breast cancer, bone metastasis and malignant lymphoma (6)(7)(8)(9)(10)(11)(12)(13). DWIBS is not commonly used to detect abdominal solid cancer, since the anatomical analysis of these tumors can be difficult and respiratory movement makes the image obscure (14,15).…”