Diffusion-Weighted MR Imaging of the Benign Hepatic Focal Lesions

El‐Badrawy, Adel; Ashmallah, Germeen Albair; Tawfik, Ahmed; Abdelfattah, Sherif; Salah-Eldin, Manal; Azmy, Emad; El-Karef, Amro; G, Salem; Farouk, Omar

doi:10.4236/ojrad.2014.41018

Cited by 3 publications

(4 citation statements)

References 26 publications

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“…In the present study, out of 40 cases, maximum number of cases were in age group of 41-60 years .Malignant lesions showed male preponderance with male to female ratio of 1.8:1 and benign lesions showed female preponderance with male to female ratio of 0.7:1,as similar to that reported in previous studies. [7][8][9][10] more number of lesions were found in right lobe of liver than left lobe, Similar to existing studies. [7,10] Out of all lesions maximum were malignant, positive correlation was seen with other studies.…”

Section: Discussionsupporting

confidence: 80%

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Role of Magnetic Resonance Diffusion Imaging in Differentiation of Malignant and Benign Hepatic Focal Lesions

Kumaraswamy¹

2019

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Background: With the advances in magnetic resonance imaging (MR) technology, diffusion-weighted magnetic resonance imaging (DWI) can be used in further characterization of liver lesions and differentiating malignant and benign lesions. Aims: The purpose of this study was to evaluate focal hepatic lesions using Diffusion Weighted Magnetic resonance imaging and calculate apparent diffusion coefficient (ADC) values, to determine if focal hepatic lesions could be differentiated as benign or malignant by diffusion weighted imaging and ADC maps. Histopathological correlation wherever possible. Material and Methods: This study was carried out on 40 patients in Department of Radiodiagnosis,

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Section: Discussionsupporting

confidence: 80%

“…[7,10] Out of all lesions maximum were malignant, positive correlation was seen with other studies. [8,9] which also showed predominance of malignant lesions. In the present study the number of patients having single lesion was equal to number of patients having multiple lesions and there was no predominance of either groups.…”

Section: Discussionmentioning

confidence: 91%

Role of Magnetic Resonance Diffusion Imaging in Differentiation of Malignant and Benign Hepatic Focal Lesions

Kumaraswamy¹

2019

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“…However, there are some studies that reported similar ADC values of solid benign lesions (focal nodular hyperplasia and adenomas) and malignant lesions (metastases, hepatocellular carcinoma) [21,22]. Mean ADC values reported in this study are lower than what is reported in some previous studies [22,23].Variability in ADC values reported in studies is probably due to imaging parameters such as b-value selection or different techniques for respiratory compensation, either breath-hold or respiratory triggering [24]. In this investigation, the respiratory-triggered technique has been chosen for breathing compensation.…”

Section: Discussioncontrasting

confidence: 50%

Evaluation of Respiratory Triggered Diffusion-Weighted MRI with Three b-Values Compared to ADC Map and Fast Spin Echo Heavily T2W in Differential Diagnosis of Hemangioma from Malignant Liver Lesions

Khorram

Faeghi

Jafarisepehr

et al. 2018

Journal of Medical Imaging and Radiation Sciences

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The goal of this study was to evaluate the ability of diffusion-weighted imaging (DWI) with three different b-values compared to apparent diffusion coefficient (ADC) map and fast spin echo heavily T 2 weighted (FSE-HT 2 W) in differential diagnosis of hemangioma from malignant liver lesions. Methods: Fifty-four liver lesions in 20 patients (12 females and eight males: mean age of 52 AE 12.3 years) were examined in this study. FSE-HT 2 W with breath-hold technique and DWI using respiratory triggered with three different b-values (50,400 and 800 s/mm 2) were performed on all patients. Mean ADC values were calculated from each lesion. Agreement levels of each sequence with standard of reference were compared by constructing the receiver operating characteristics (ROC) curve and calculation of the area under the ROC curve. Results: ADC maps had the largest area under the ROC curve and also the most agreement with the standard of reference. DWI obtained with high b-value (b-800 s/mm 2) and FSE-HT 2 W technique were ranked next, respectively. Hemangiomas had significantly higher ADC values than malignant liver lesions (P ¼ .001). No significant differences were seen in gender, age, and lesion size between two lesion groups. Conclusions: ADC maps and DWI in high b-values are more successful than FSE-HT 2 W technique in differential diagnosis of hemangioma from malignant liver lesions.

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“…Conventional diffusion-weighted imaging (DWI) has been widely reported to be useful in hepatic magnetic resonance imaging (MRI) for tumor detection and differentiation and the evaluation of infections, 1,2 yet it requires significant time for the imaging process. Although many imaging methods, such as long echo-train imaging, parallel imaging, and compressed sensing have significantly reduced the acquisition time, 3 general DWI is based on spin-echo T2-weighted or echo-planar imaging, which requires a sufficiently long TR 4 .…”

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confidence: 99%

Evaluating of the Quality of Hepatic Diffusion Weighted Imaging Using Multiband Imaging With Variable-Rate Selective Excitation

Yoshida

Nakaura

Morita

et al. 2022

J Comput Assist Tomogr

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Objective: To assess the image quality of diffusion-weighted imaging (DWI) using multiband (MB) imaging with variable-rate selective excitation (VERSE) and compare it to conventional DWI. Methods:We retrospectively evaluated hepatic DWI images of patients (n = 76) according to either the conventional method (SENSE, acceleration factor = 2) (n = 38) or fast scanning method (MB imaging with VERSE, acceleration factor = 2 Â 2) (n = 38). We also conducted a volunteer study (n = 15) for those scanning methods. During quantitative analysis, the signal-to-noise ratio (SNR), apparent diffusion coefficient values, and contrast in the liver, spleen, and spinal cord were compared between the 2 groups. During qualitative analysis, all images were independently and blindly evaluated by 2 board-certified radiologists. The image contrast, noise, artifacts, and sharpness were assessed, and the performance of classification was measured using receiver operating characteristic curve analysis. Results:In the retrospective study, the SNRs of the hepatic parenchyma and spinal cord between the 2 protocols were significantly different (liver, 8.9 [interquartile range {IQR}, 7.6-12.2] vs 13.0 [IQR, 10.0-16.7]; P < 0.001 and spinal cord, 6.0 [IQR,]; P < 0.02). No significant differences between the 2 protocols in the other retrospective analyses were noted. In the receiver operating characteristic curve analysis, area under the curve was 0.49 (95% confidence intervals, 0.40-0.58). Conclusion:Multiband VERSE reduced scan time and SNR of hepatic DWI; however, subjective image quality parameters were not significantly impacted.

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Diffusion-Weighted MR Imaging of the Benign Hepatic Focal Lesions

Abstract: A. El-Badrawy et al.

Cited by 3 publications

References 26 publications

Role of Magnetic Resonance Diffusion Imaging in Differentiation of Malignant and Benign Hepatic Focal Lesions

Role of Magnetic Resonance Diffusion Imaging in Differentiation of Malignant and Benign Hepatic Focal Lesions

Evaluation of Respiratory Triggered Diffusion-Weighted MRI with Three b-Values Compared to ADC Map and Fast Spin Echo Heavily T2W in Differential Diagnosis of Hemangioma from Malignant Liver Lesions

Evaluating of the Quality of Hepatic Diffusion Weighted Imaging Using Multiband Imaging With Variable-Rate Selective Excitation

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