Diffusion-Weighted MR Imaging Findings of Cortical Vein Thrombosis at 3 T

Yıldız, Mehmet Erdem; Özcan, Ümit Aksoy; Turk, Aquilla S; Ulus, Özden Sila; Erzen, Canan; Di̇nçer, Alp

doi:10.1007/s00062-014-0301-y

Cited by 14 publications

(11 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Among the included studies, 16 were retrospective in desig ns [ 2 , 3 , 6 , 8 , 10 , 11 , 13 , 18 , 20 - 23 , 25 , 26 , 36 , 37 ] and three were the case reports [ 7 , 15 , 33 ]. In all, 443 patients with CVT were subjected to DWI examinations in these studies.…”

Section: Resultsmentioning

confidence: 99%

“…Although, we have observed that hyperintense signal on DWI is associated with low sensitivity to detect CVT, however, the hyperintense signal on DWI had high specificity for CVT. It is suggested that DWI can provide an additional clue for the diagnosis of CVT which could be important in clinically unsuspected patients [ 37 ]. By using DWI, Favrole et al [ 11 ] detected 20 occluded veins or sinuses in 12 patients (41%) with recent CVT and suggested that the presence of hyperintense signal on DWI in occluded veins at the time of diagnosis might be predictive of a low rate of vessel recanalization 2 or 3 months later.…”

Section: Discussionmentioning

confidence: 99%

“…It has also been suggested that DWI may provide an additional clue to CVT diagnosis in clinically unsuspected patients after standard MRI scans but without sensitive MRI sequences such as contrast enhanced MRV or T2-weighted gradient recalled echo. Careful examination of cortical surface on diffusion MRI for clot signal or clot susceptibility signal can give additional information when CVT is not suspected on routine T1 or T2 or fluid-attenuated inversion recovery sequence [ 37 ]. The presence of hyperintense signal on DWI has also been found to be predictive of clinical deterioration during hospital stay [ 31 ].…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Diffusion-Weighted Magnetic Resonance Imaging in the Diagnosis of Cerebral Venous Thrombosis : A Meta-Analysis

Jin

Tian

et al. 2021

J Korean Neurosurg Soc

View full text Add to dashboard Cite

Objective : A role of diffusion-weighted imaging (DWI) in the diagnosis of cerebral venous thrombosis (CVT) is not wellunderstood. This study evaluates the effectiveness of DWI in the diagnosis of CVT. Methods : Literature search was conducted in electronic databases for the identification of studies which reported the outcomes of patients subjected to DWI for CVT diagnosis. Random-effects meta-analyses were performed to achieve overall estimates of important diagnostic efficiency indices including hyperintense signal rate, the sensitivity and specificity of DWI in diagnosing CVT, and the apparent diffusion coefficient (ADC) of DWI signal areas and surrounding tissue. Results : Nineteen studies (443 patients with 856 CVTs; age 40 years [95% confidence interval (CI), 33 to 43]; 28% males [95% CI, 18 to 38]; symptom onset to DWI time 4.6 days [95% CI, 2.3 to 6.9]) were included. Hyperintense signals on DWI were detected in 40% (95% CI, 26 to 55) of the cases. The sensitivity of DWI for detecting CVT was 22% (95% CI, 11 to 34) but specificity was 98% (95% CI, 95 to 100). ADC values were quite heterogenous in DWI signal areas. However, generally the ADC values were lower in DWI signal areas than in surrounding normal areas (mean difference−0.33×10 -3 mm 2 /s [95% CI, −0.44 to −0.23]; p<0.00001). Conclusion : DWI has a low sensitivity in detecting CVT and thus has a high risk of missing many CVT cases. However, because of its high specificity, it may have supporting and exploratory roles in CVT diagnosis.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Diffusion-Weighted Magnetic Resonance Imaging in the Diagnosis of Cerebral Venous Thrombosis : A Meta-Analysis

Jin

Tian

et al. 2021

J Korean Neurosurg Soc

View full text Add to dashboard Cite

show abstract

“…Since susceptibility effects are well known to disappear with the formation of extracellular methemoglobin, it seems to be the main reason for the non-visualization of COVT in these 2 cases [ 3 , 4 , 8 ]. Fortunately, the clots were easily identifiable on T1 TSE, DWI and FLAIR sequences in both cases [ 17 ]. Our results highlight that SWI is a vital sequence to evaluate COVT as it can identify the majority of COVT on its own.…”

Section: Discussionmentioning

confidence: 99%

Detection of cerebral cortical vein thrombosis with high-resolution susceptibility weighted imaging — A comparison with MR venography and standard MR sequences

et al. 2023

View full text Add to dashboard Cite

Purpose Comparison of the performance of high-resolution susceptibility weighted imaging with standard MR sequences and MR venography to identify cortical vein clots. Methods A retrospective review of 51 consecutive cases of cerebral venous thrombosis and 27 controls was performed with independent analysis of all MR sequences. Reference standard was obtained with consensus in a separate session by reviewing all MR sequences together. Results Cortical vein clots were observed in 30 cases including 9 males and 21 females in the age range of 1 month to 70 years (Mean 34.9 ± 20.2 years). Sensitivity, specificity, negative predictive value, positive predictive value and accuracy of susceptibility weighted imaging for the identification of cortical vein clots were 0.93, 1.0, 1.0, 0.96 and 0.97 respectively. For all other sequences, sensitivity ranged from 0.06 to 0.39 and accuracy from 0.60 to 0.73. Combination of all sequences yielded a value of 1.0 for sensitivity, specificity, positive predictive value, negative predictive value and accuracy for the detection of cortical vein clots. Significant result for area under the receiver operating curve was observed only for SWI with a value of 0.91 ( p - .000). Conclusion Susceptibility weighted imaging demonstrates the best sensitivity and accuracy among standard MR sequences including MR venography for the detection of early stage cortical vein clots. However, it needs to be interpreted in combination with other MR sequences for the most accurate evaluation of cortical vein clots. Supplementary Information The online version contains supplementary material available at 10.1007/s00234-023-03123-y.

show abstract

“…On MRI, it has variable clot signal depending on the age of the clot, field strength, haemoglobin level, image sequence and other factors. There should be absent flow signal on the MR venogram and possible diffusion weighted imaging (DWI) changes due to associated infarction 18. Mortality has been reducing over the last few years, probably due to early recognition and treatment with anticoagulants 19…”

Section: Venous Infarctionmentioning

confidence: 99%

A pictorial review of imaging in paediatric stroke

Johns

Kolla

Hart

et al. 2016

Postgraduate Medical Journal

View full text Add to dashboard Cite

Stroke is recognised as an important disease in adults. Paediatric stroke is less understood, yet still an important cause of morbidity and mortality, with an incidence of 5 per 100 000 children and is one of the top 10 leading causes of death in children. In adults the vast majority of strokes are ischaemic, whereas in children haemorrhage makes up half the cases. The incidence of neonatal stroke is much higher, at up to 45 per 100 000 population; however, the underlying causes are less understood. This paper acts as a guide to the different causes of stroke with the key differences on imaging discussed.

show abstract

Diffusion-Weighted MR Imaging Findings of Cortical Vein Thrombosis at 3 T

Abstract: Besides the hyperintense CS, with additional evaluation of the presence of CSS, DWI can provide an additional clue in CVT patients and may suggest its diagnosis, which is important in clinically unsuspected patients.

Cited by 14 publications

References 23 publications

Diffusion-Weighted Magnetic Resonance Imaging in the Diagnosis of Cerebral Venous Thrombosis : A Meta-Analysis

Diffusion-Weighted Magnetic Resonance Imaging in the Diagnosis of Cerebral Venous Thrombosis : A Meta-Analysis

Detection of cerebral cortical vein thrombosis with high-resolution susceptibility weighted imaging — A comparison with MR venography and standard MR sequences

A pictorial review of imaging in paediatric stroke

Contact Info

Product

Resources

About