Diffusion-weighted imaging of bone marrow pathologies

Comparison of Qualitative and Quantitative Evaluation of Diffusion-Weighted MRI and Chemical-Shift Imaging in the Differentiation of Benign and Malignant Vertebral Body Fractures

“…With increasing b values, the (relative) background noise in our study was higher, as has also been reported in previous studies [14]. At b values of 50 and 250 s/mm 2 , most malignant lesions as well as benign lesions were hyperintense probably because of the T2 shine-through effect [22].…”

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1083of signal intensities (SIs) on diffusion-weighted (DW) steady-state free-precession (SSFP), echo-planar imaging (EPI), single-shot turbo spin-echo (TSE), and opposed-phase sequences as well as the quantitative measurement of apparent diffusion coefficients (ADCs) and the value of quantitative chemical-shift imaging to improve specificity [5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24]. Because there have been partially contradicting statements about the value of these techniques and there is still uncertainty whether quantification is really necessary and how it improves specificity,

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High Signal in Bone Marrow on Diffusion‐Weighted Imaging of Female Pelvis: Correlation With Anemia and Fibroid‐Associated Symptoms

“…DWI is applied to the bone marrow for assessing various bony pathologies, primarily through direct visual differentiation of the signal contrast between normal and pathological processes. Many pathological processes can cause an increase in the SI of DWI, including bone edema, infection, and neoplasm . However the SI of DWI is influenced by the T 1 and T 2 signals and susceptibility effects and therefore cannot readily differentiate bone edema from hypercellular pathologies …”

Multiparametric data collection of animal tissues in magnetic resonance imaging

“…These changes obscure the distinct appearance of fatty bone marrow and serve as early indicators of pathology, which makes this imaging technique a very sensitive diagnostic tool [6] and [7].…”