Diffusion-weighted imaging: basic concepts and application in cerebral stroke and head trauma

Tagm, Huisman

doi:10.1016/s0899-7071(03)00295-x

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2019

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“…Diffusion‐weighted MRI (DWI) is a unique MRI contrast that is used in the diagnosis and treatment of conditions such as stroke, toxic‐metabolic disorders, seizure, trauma, demyelination, tumors, infection, and others characterized by microstructural changes . DWI can help to detect subtle lesions, characterize tissue physiology, refine diagnosis, and monitor disease time course.…”

Section: Introductionmentioning

confidence: 99%

The quest for high spatial resolution diffusion‐weighted imaging of the human brain in vivo

Holdsworth

O’Halloran²,

Setsompop

2019

NMR in Biomedicine

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Diffusion‐weighted imaging, a contrast unique to MRI, is used for assessment of tissue microstructure in vivo. However, this exquisite sensitivity to finer scales far above imaging resolution comes at the cost of vulnerability to errors caused by sources of motion other than diffusion motion. Addressing the issue of motion has traditionally limited diffusion‐weighted imaging to a few acquisition techniques and, as a consequence, to poorer spatial resolution than other MRI applications. Advances in MRI imaging methodology have allowed diffusion‐weighted MRI to push to ever higher spatial resolution. In this review we focus on the pulse sequences and associated techniques under development that have pushed the limits of image quality and spatial resolution in diffusion‐weighted MRI.

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